Prop-2-enyl 3,3-diamino-2-methylprop-2-enoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 乙烯基酰胺
• 英文名称: Prop-2-enyl 3,3-diamino-2-methylprop-2-enoate
• 英文别名: prop-2-enyl 3,3-diamino-2-methylprop-2-enoate
• 化学式: C₇H₁₂N₂O₂
• 分子量: 156.18
• InChiKey: JWFKFQBTRTVTJM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  11
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  78.3
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• AGENT FOR IMPROVING CANCER CELL ADHESIVENESS
  申请人：Kanbara Hisashige

  公开号：US20140178890A1

  公开（公告）日：2014-06-26

  A polymer comprising a constitutional unit represented by the following formula (1) is useful because when the polymer is applied to a surface of a cancer cell enrichment filter, adhesiveness of cancer cells to the filter surface can be improved so that an enrichment ratio of the cancer cells can be improved. In the formula (1), R 1 is a hydrogen atom or a methyl group, R 2 is a methyl group or an ethyl group and m is 1 to 3.

  具有以下公式（1）所代表的构成单元的聚合物是有用的，因为当该聚合物被应用于癌细胞富集过滤器的表面时，癌细胞与过滤器表面的粘附性可以提高，从而可以提高癌细胞的富集比率。在公式（1）中，R1是氢原子或甲基基团，R2是甲基基团或乙基基团，m为1至3。
• POLYMER COMPOUND FOR MEDICAL USE AND COMPOSITION AND DEVICE USING SAME
  申请人：National University Corporation Yamagata University

  公开号：EP3124507A1

  公开（公告）日：2017-02-01

  The present invention provides a polymer compound that can be expected to inhibit activation of a coagulation system, a complement system or a platelet system when brought into contact with in vivo tissue and/or blood since the compound is capable of containing intermediate water, and a composition and a device using the same. This problem is solved by a polymer compound containing a repeating unit represented by general formula (A), and used in contact with in vivo tissue and/or blood, in which in a process in which the polymer compound caused to contain water in a prescribed water content is cooled to -100°C and thereafter heated at a temperature rise rate of 5.0°C/min, a temperature region where exothermicity occurs is present in the range of -80°C or more and -25°C or less, and a temperature region where endothermicity occurs is present in the range of -25°C or more and lower than 0°C: wherein R represents a hydrocarbon group having 1 to 20 carbon atoms.

  本发明提供了一种聚合物化合物，由于该化合物能够含有中间水，因此当与体内组织和/或血液接触时，可望抑制凝血系统、补体系统或血小板系统的活化，本发明还提供了使用该化合物的组合物和装置。解决这一问题的方法是一种含有通式(A)代表的重复单元的聚合物化合物，用于与体内组织和/或血液接触，在此过程中，将含有规定含水量的聚合物化合物冷却到-100℃，然后以5.0℃/分钟的升温速率加热，放热的温度区域在-80℃或以上和-25℃或以下的范围内，而内热的温度区域在-25℃或以上和低于0℃的范围内： 其中 R 代表具有 1 至 20 个碳原子的烃基。
• US9372136B2
  申请人：——

  公开号：US9372136B2

  公开（公告）日：2016-06-21