(2R)-5-(3-aminopropyl)-2-(sulfanylmethyl)azepan-3-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环庚烷
• 英文名称: (2R)-5-(3-aminopropyl)-2-(sulfanylmethyl)azepan-3-one
• 化学式: C₁₀H₂₀N₂OS
• 分子量: 216.35
• InChiKey: VOAKLTQHAGBQMC-GKAPJAKFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  56.1
• 氢给体数：
  3
• 氢受体数：
  4

文献信息

• Pharmaceutical Composition
  申请人：Moberg Kerstin Uvnäs

  公开号：US20140171369A1

  公开（公告）日：2014-06-19

  The present invention relates to a novel pharmaceutical composition comprising oxytocin and/or one or more fragment(s) and/or variant(s) thereof and at least one non-ionic cellulose ether, such as hydroxypropylmethylcellulose, said pharmaceutical composition having a low pH. The present pharmaceutical composition has been shown to provide an exceptionally suitable environment for oxytocin, as the stability thereof has increased significantly as compared to previous compositions with this molecule. The pharmaceutical composition according to the invention can be used for medical purposes, such as in the treatment of climacteric disorders.
• US9034821B2
  申请人：——

  公开号：US9034821B2

  公开（公告）日：2015-05-19