N-methyl-N,N-bis(methoxydimethylsilylmethyl)amine | 53677-62-6

• 分子结构分类: 有机化合物 - 有机金属化合物 - 有机类金属化合物
• 英文名称: N-methyl-N,N-bis(methoxydimethylsilylmethyl)amine
• 英文别名: bis[dimethyl(methoxy)silylmethyl]methylamine；1-[methoxy(dimethyl)silyl]-N-[[methoxy(dimethyl)silyl]methyl]-N-methylmethanamine
• CAS: 53677-62-6
• 化学式: C₉H₂₅NO₂Si₂
• 分子量: 235.474
• InChiKey: QEFJDCVRGVVFAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  N-methyl-N,N-bis(methoxydimethylsilylmethyl)amine 在 水 作用下， 以 苯 为溶剂， 反应 3.0h， 以80%的产率得到2,2,4,6,6-pentamethyl-1,4,2,6-oxaazadisilazane
  参考文献：
  名称：

  4-Alkyl-2,2,6,6-tetramethyl-1,4,2,6-oxaazadisilinanes: synthesis, structure, and conformational analysis

  摘要：

  Abstract4‐Alkyl‐2,2,6,6‐tetramethyl‐1,4,2,6‐oxaazadisilinanes RN[CH2Si(Me)2]2O [R = Me (1), i‐Pr (2)] were synthesized by two methods which provided good yields up to 84%. Low temperature NMR study of compounds (1) and (2) revealed a frozen ring inversion with the energy barriers of 8.5 and 7.7 kcal/mol at 163 and 143 K, respectively, which is substantially lower than that for their carbon analog, N‐methylmorpholine. DFT calculations performed on the example of molecule (1) showed that NMeax conformer to exist in the sofa conformation with the coplanar fragment CSiOSiC, and its NMeeq conformer in a flattened chair conformation. Copyright © 2009 John Wiley & Sons, Ltd.

  DOI：

  10.1002/poc.1605
• 作为产物：
  描述：

  氯甲基(二甲基)甲氧基硅烷 、 甲胺 生成 N-methyl-N,N-bis(methoxydimethylsilylmethyl)amine
  参考文献：
  名称：

  Mironov,V.F. et al., Journal of general chemistry of the USSR, 1974, vol. 44, p. 1468 - 1472

  摘要：

  DOI：

文献信息

• NMR, IR, and ESR spectroscopic investigation of reaction of<i>α</i>-silylamines with carbon tetrachloride
  作者：Nataliya F. Lazareva、Tamara I. Vakul'skaya、Igor M. Lazarev

  DOI：10.1002/poc.1442

  日期：2009.2

  α‐silylamine hydrochloride salts in 92–98% yields. The influence of structure of α‐silylamines and solvent on the degree of conversion was displayed. The interaction of α‐silylamines with CCl4 was studied by NMR, ESR, and IR spectroscopy. C‐centered radicals of α‐silylamines were detected by ESR spectroscopy with spin traps (MNP, ND, and PBN) in reaction mixtures in CH3CN and C6H6 and it show the radical character

  本文报道了α-甲硅烷基胺与CCl 4反应的高反应性。与Et 3 N不同，α-甲硅烷基胺在日光照射下迅速与CCl 4反应，以92-98％的产率形成α-甲硅烷基胺盐酸盐。显示了α-甲硅烷基胺和溶剂的结构对转化率的影响。通过NMR，ESR和IR光谱研究了α-甲硅烷基胺与CCl 4的相互作用。通过ESR光谱用CH 3 CN和C的反应混合物中的自旋阱（MNP，ND和PBN）检测到α-甲硅烷基胺的C中心自由基6 H 6和它显示了该反应的自由基特征。CH 3 CN和C 6 H 6均用作该反应的溶剂和试剂。讨论了α-甲硅烷基胺与CCl 4相互作用的机理。版权所有©2008 John Wiley＆Sons，Ltd.
• Mironov,V.F. et al., Journal of general chemistry of the USSR, 1974, vol. 44, p. 1468 - 1472
  作者：Mironov,V.F. et al.

  DOI：——

  日期：——
• 4-Alkyl-2,2,6,6-tetramethyl-1,4,2,6-oxaazadisilinanes: synthesis, structure, and conformational analysis
  作者：Nataliya F. Lazareva、Bagrat A. Shainyan、Erich Kleinpeter

  DOI：10.1002/poc.1605

  日期：2010.1

  Abstract4‐Alkyl‐2,2,6,6‐tetramethyl‐1,4,2,6‐oxaazadisilinanes RN[CH2Si(Me)2]2O [R = Me (1), i‐Pr (2)] were synthesized by two methods which provided good yields up to 84%. Low temperature NMR study of compounds (1) and (2) revealed a frozen ring inversion with the energy barriers of 8.5 and 7.7 kcal/mol at 163 and 143 K, respectively, which is substantially lower than that for their carbon analog, N‐methylmorpholine. DFT calculations performed on the example of molecule (1) showed that NMeax conformer to exist in the sofa conformation with the coplanar fragment CSiOSiC, and its NMeeq conformer in a flattened chair conformation. Copyright © 2009 John Wiley & Sons, Ltd.