7-Azabicyclo[4.1.0]heptane;methanesulfonic acid

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环庚烷
• 英文名称: 7-Azabicyclo[4.1.0]heptane;methanesulfonic acid
• 英文别名: 7-azabicyclo[4.1.0]heptane;methanesulfonic acid
• 化学式: C7H15NO3S
• 分子量: 193.27
• InChiKey: OOXAEFCFYCLMOX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.4
• 重原子数：
  12
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  84.7
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Methods of detecting influenza virus
  申请人：University of Cincinnati

  公开号：US10408836B2

  公开（公告）日：2019-09-10

  Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method including measuring the enzymatic activity of neuraminidase (NA) in the sample under one or more differentiating conditions selected from the group consisting of pH, binding to anti-NanA antibody, size exclusion, hemagglutinin (HA) binding, chemical inhibition, and combinations thereof.

  本文提供了一种检测样品中是否存在流感病毒的方法，同时最大限度地减少因样品中存在一种或多种其他病原体而导致的假阳性，该方法包括在一种或多种选自 pH 值、与抗 NanA 抗体的结合、尺寸排除、血凝素（HA）结合、化学抑制及其组合的区分条件下测量样品中神经氨酸酶（NA）的酶活性。
• US20140272942A1
  申请人：——

  公开号：US20140272942A1

  公开（公告）日：2014-09-18
• Methods of Detecting Influenza Virus
  申请人：University of Cincinnati

  公开号：US20170016899A1

  公开（公告）日：2017-01-19

  Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method including measuring the enzymatic activity of neuraminidase (NA) in the sample under one or more differentiating conditions selected from the group consisting of pH, binding to anti-NanA antibody, size exclusion, hemagglutinin (HA) binding, chemical inhibition, and combinations thereof.
• US9487816B2
  申请人：——

  公开号：US9487816B2

  公开（公告）日：2016-11-08
• [EN] METHODS OF DETECTING INFLUENZA VIRUS<br/>[FR] PROCÉDÉS DE DÉTECTION DU VIRUS DE LA GRIPPE
  申请人：UNIV CINCINNATI

  公开号：WO2014143864A2

  公开（公告）日：2014-09-18

  Provided herein is a method of detecting the presence of influenza virus in a sample while minimizing false positives due to presence of one or more other pathogens in the sample, the method including measuring the enzymatic activity of neuraminidase (NA) in the sample under one or more differentiating conditions selected from the group consisting of pH, binding to anti-NanA antibody, size exclusion, hemagglutinin (HA) binding, chemical inhibition, and combinations thereof.