6-(7-(((6-methylpyridin-2-yl)methyl)amino)thianthren1-yl)-4-morpholinopyridin-2(1H)-one

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二硫类化合物
• 英文名称: 6-(7-(((6-methylpyridin-2-yl)methyl)amino)thianthren1-yl)-4-morpholinopyridin-2(1H)-one
• 英文别名: 6-[7-[(6-methylpyridin-2-yl)methylamino]thianthren-1-yl]-4-morpholin-4-yl-1H-pyridin-2-one
• 化学式: C₂₈H₂₆N₄O₂S₂
• 分子量: 514.672
• InChiKey: JURCPKDLCZHVRK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  36
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.21
• 拓扑面积：
  117
• 氢给体数：
  2
• 氢受体数：
  7

文献信息

• NOVEL MORPHOLINE DERIVATIVE OR SALT THEREOF
  申请人：Fujifilm Corporation

  公开号：EP3042900A1

  公开（公告）日：2016-07-13

  There is provided a morpholine derivative represented by General Formula [1A] or a salt thereof. (In the formula, a ring A represents a ring represented by General Formula [I]; * represents a bonding position; Z2 represents CH or the like; Z1 represents CR6 or the like; R6 represents a hydrogen atom or the like; X1 represents CHR7 or the like; R7 represents a hydrogen atom or the like; X2 represents CH2 or the like; R1 and R2 are the same as or different from each other, and each of R1 and R2 represents a hydrogen atom or the like; R3, R4 and R5 are the same as or different from each other, and each of R3, R4, and R5 represents a hydrogen atom, NRaRb, or the like; and each of Ra and Rb represents a hydrogen atom, a C1-8 alkyl group which may have a substituent, or the like.)

  提供了通式[1A]代表的吗啉衍生物或其盐。 (式中，环 A 代表通式[I]所代表的环；* 代表键合位置；Z2 代表 CH 或类似物；Z1 代表 CR6 或类似物；R6 代表氢原子或类似物；X1 代表 CHR7 或类似物；R7 代表氢原子或类似物；X2 代表 CH2 或类似物；R1和R2彼此相同或不同，且R1和R2各自代表氢原子或类似物；R3、R4和R5彼此相同或不同，且R3、R4和R5各自代表氢原子、NRaRb或类似物；Ra和Rb各自代表氢原子、可能具有取代基的C1-8烷基或类似物。)