9H-fluoren-9-ylmethyl N-[(4R)-4-[2-[[4-[[9-[(2R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[[(2R,5R)-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-5-[(6R)-2-[4-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]butanoylamino]-6-hydroxy-3,6-dihydropurin-9-yl]oxolan-2-yl]methoxy]phosphanyl]oxyoxolan-2-yl]purin-6-yl]carbamoyl]phenyl]methylamino]-2-oxoethoxy]-4-hydroxybutyl]-N-methylcarbamate

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 9H-fluoren-9-ylmethyl N-[(4R)-4-[2-[[4-[[9-[(2R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-[2-cyanoethoxy-[[(2R,5R)-3-[2-cyanoethoxy-[di(propan-2-yl)amino]phosphanyl]oxy-5-[(6R)-2-[4-[9H-fluoren-9-ylmethoxycarbonyl(methyl)amino]butanoylamino]-6-hydroxy-3,6-dihydropurin-9-yl]oxolan-2-yl]methoxy]phosphanyl]oxyoxolan-2-yl]purin-6-yl]carbamoyl]phenyl]methylamino]-2-oxoethoxy]-4-hydroxybutyl]-N-methylcarbamate
• 化学式: C₁₀₃H₁₁₄N₁₆O₂₀P₂
• 分子量: 1958.0
• InChiKey: AHHKEGPUUXLPAP-OYCSOPAWSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10.5
• 重原子数：
  141
• 可旋转键数：
  48
• 环数：
  16.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  425
• 氢给体数：
  6
• 氢受体数：
  28

文献信息

• NUCLEIC ACID SYNTHESIZING DIMER AMIDITE AND NUCLEIC ACID SYNTHESIZING METHOD
  申请人：Fujihara Tsuyoshi

  公开号：US20100197902A1

  公开（公告）日：2010-08-05

  A nucleic acid synthesizing dimer amidite including two nucleoside compounds, wherein the two nucleoside compounds are linked with each other via a phosphite triester bond.