1,1-Bis(4-aminophenyl)-1-<4-(4-bromophenoxy)phenyl>-2,2,2-trifluoroethane | 154519-98-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 三苯基化合物
• 英文名称: 1,1-Bis(4-aminophenyl)-1-<4-(4-bromophenoxy)phenyl>-2,2,2-trifluoroethane
• 英文别名: 4-[1-(4-Aminophenyl)-1-[4-(4-bromophenoxy)phenyl]-2,2,2-trifluoroethyl]aniline
• CAS: 154519-98-9
• 化学式: C₂₆H₂₀BrF₃N₂O
• 分子量: 513.357
• InChiKey: CNRXJXOIHKDLRW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  33
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  61.3
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  1,1-Bis(4-aminophenyl)-1-<4-(4-bromophenoxy)phenyl>-2,2,2-trifluoroethane 在 四(三苯基膦)钯 copper(l) iodide 、 三苯基膦 作用下， 以 various solvent(s) 为溶剂， 反应 41.0h， 生成 1,1-Bis(4-aminophenyl)-1-<4-(4-ethynylphenoxy)phenyl>-2,2,2-trifluoroethane
  参考文献：
  名称：

  Synthesis of Difunctional Triarylethanes with Pendent Ethynyl Groups: Monomers for Crosslinkable Condensation Polymers1

  摘要：

  Synthetic schemes have been developed and optimized for the preparation of groups of 4,4'-diamino- and 4,4'-dihydroxytriarylethanes with an ethynyl group pendent on the third aryl group. Palladium(0)-catalyzed reaction of an aryl halide moiety with an acetylene is used for the attachment of the ethynyl group. The third aryl group is either a phenyl or a phenoxyphenyl group, while the other end of the ethynyl group is either unprotected or bears an n-butyl or phenyl group. The variations in the structure of the third aryl group and the cap on its acetylene group are chosen to probe their influence on the mechanical properties of the resulting crosslinked thermoplastics.

  DOI：

  10.1021/jo00088a035
• 作为产物：
  描述：

  苯胺 、 4-(4-Bromophenoxy)trifluoroacetophenone 以70%的产率得到1,1-Bis(4-aminophenyl)-1-<4-(4-bromophenoxy)phenyl>-2,2,2-trifluoroethane
  参考文献：
  名称：

  Synthesis of Difunctional Triarylethanes with Pendent Ethynyl Groups: Monomers for Crosslinkable Condensation Polymers1

  摘要：

  Synthetic schemes have been developed and optimized for the preparation of groups of 4,4'-diamino- and 4,4'-dihydroxytriarylethanes with an ethynyl group pendent on the third aryl group. Palladium(0)-catalyzed reaction of an aryl halide moiety with an acetylene is used for the attachment of the ethynyl group. The third aryl group is either a phenyl or a phenoxyphenyl group, while the other end of the ethynyl group is either unprotected or bears an n-butyl or phenyl group. The variations in the structure of the third aryl group and the cap on its acetylene group are chosen to probe their influence on the mechanical properties of the resulting crosslinked thermoplastics.

  DOI：

  10.1021/jo00088a035

文献信息

• Ansong Omari, Antoine Miquel D., Nwokogu Godson C., J. Org. Chem., (1995) N 9, S 2506-2510
  作者：Ansong Omari, Antoine Miquel D., Nwokogu Godson C.

  DOI：——

  日期：——
• Synthesis of Difunctional Triarylethanes with Pendent Ethynyl Groups: Monomers for Crosslinkable Condensation Polymers1
  作者：Omari Ansong、Miquel D. Antoine、Godson C. Nwokogu、Paul M. Hergenrother

  DOI：10.1021/jo00088a035

  日期：1994.5

  Synthetic schemes have been developed and optimized for the preparation of groups of 4,4'-diamino- and 4,4'-dihydroxytriarylethanes with an ethynyl group pendent on the third aryl group. Palladium(0)-catalyzed reaction of an aryl halide moiety with an acetylene is used for the attachment of the ethynyl group. The third aryl group is either a phenyl or a phenoxyphenyl group, while the other end of the ethynyl group is either unprotected or bears an n-butyl or phenyl group. The variations in the structure of the third aryl group and the cap on its acetylene group are chosen to probe their influence on the mechanical properties of the resulting crosslinked thermoplastics.