N-methylsulfanylhexan-3-amine

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机次磺酸及其衍生物
• 英文名称: N-methylsulfanylhexan-3-amine
• 化学式: C₇H₁₇NS
• 分子量: 147.28
• InChiKey: XPOVJTROYBZPQP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  9
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

文献信息

• Treatment of skin lesions and pruritus in prurigo nodularis patients
  申请人：GALDERMA HOLDING SA

  公开号：US11236157B2

  公开（公告）日：2022-02-01

  Disclosed herein are methods for selectively treating pruritus in a subject having chronic prurigo (CP), including prurigo nodularis (PN), pharmaceutical compositions for use in the treatment of pruritus in a subject having CP or PN, uses of nemolizumab or an equivalent thereof in the manufacture of a medicament for the treatment of pruritus in a subject having CP or PN.

  本文公开了选择性治疗慢性瘙痒症（CP）（包括结节性瘙痒症（PN））患者瘙痒症的方法、用于治疗CP或PN患者瘙痒症的药物组合物、在制造治疗CP或PN患者瘙痒症的药物中使用尼妥珠单抗或其等效物的方法。
• TREATMENT OF SKIN LESIONS AND PRURITUS IN PRURIGO NODULARIS PATIENTS
  申请人：CHUGAI SEIYAKU KABUSHIKI KAISHA

  公开号：US20200239563A1

  公开（公告）日：2020-07-30

  Disclosed herein are methods for selectively treating pruritus in a subject having chronic prurigo (CP), including prurigo nodularis (PN), pharmaceutical compositions for use in the treatment of pruritus in a subject having CP or PN, uses of nemolizumab or an equivalent thereof in the manufacture of a medicament for the treatment of pruritus in a subject having CP or PN.