1-(2,4-Difluorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 三嗪类
• 英文名称: 1-(2,4-Difluorophenyl)-6,6-dimethyl-1,3,5-triazine-2,4-diamine
• 化学式: C₁₁H₁₃F₂N₅
• 分子量: 253.25
• InChiKey: UDRBBDNKWHCUFR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  18
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  80
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• Compounds and compositions for ossification and methods related thereto
  申请人：Emory University

  公开号：US10888565B2

  公开（公告）日：2021-01-12

  The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.

  本公开涉及用于形成骨骼的化合物和组合物及其相关方法。 在一个实施方案中，本公开涉及一种包含本文公开的化合物（如 2,4-二氨基-1,3,5-三嗪衍生物或其盐类）的组合物，用于骨生长过程。 在一个典型的实施方案中，骨移植组合物被植入受试者所需骨生长或增强的部位。
• COMPOUNDS AND COMPOSITIONS FOR OSSIFICATION AND METHODS RELATED THERETO
  申请人：Emory University

  公开号：EP2605804B1

  公开（公告）日：2017-03-15
• Compounds and Compositions for Ossification and Methods Related Thereto
  申请人：Emory University

  公开号：US20170035771A1

  公开（公告）日：2017-02-09

  The disclosure relates to compounds and compositions for forming bone and methods related thereto. In one embodiment, the disclosure relates to a composition comprising a compound disclosed herein, such as 2,4-diamino-1,3,5-triazine derivatives or salts thereof, for use in bone growth processes. In a typical embodiment, a bone graft composition is implanted in a subject at a site of desired bone growth or enhancement.
• US9511071B2
  申请人：——

  公开号：US9511071B2

  公开（公告）日：2016-12-06
• US9808464B2
  申请人：——

  公开号：US9808464B2

  公开（公告）日：2017-11-07