4-(2,5-Dimethylphenylazo)-phenol | 27761-33-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 4-(2,5-Dimethylphenylazo)-phenol
• 英文别名: 4-[(2,5-Dimethylphenyl)hydrazinylidene]cyclohexa-2,5-dien-1-one；4-[(2,5-dimethylphenyl)diazenyl]phenol
• CAS: 27761-33-7
• 化学式: C₁₄H₁₄N₂O
• 分子量: 226.278
• InChiKey: SZMBWRNOKVQLLA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  45
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,5-二甲基苯胺 、 苯酚 在 bentonite GB clay 、 sodium nitrite 作用下， 反应 1.0h， 以95%的产率得到4-(2,5-Dimethylphenylazo)-phenol
  参考文献：
  名称：

  Modified Clays as Efficient Acid–Base Catalyst Systems for Diazotization and Diazocoupling Reactions

  摘要：

  Diazotization and diazocoupling reactions of aniline and its substituted derivatives with phenol and other aromatic amines over ecofriendly clay catalysts is described. This inexpensive, noncorrosive and reusable catalysts were found to exhibit bifunctional catalytic properties for these reactions. No considerable decrease in the efficiency of the catalysts were observed after five cycles of operation. The new method totally avoids the use of acids and alkalies.

  DOI：

  10.1081/scc-120016343

文献信息

• Modified Clays as Efficient Acid–Base Catalyst Systems for Diazotization and Diazocoupling Reactions
  作者：Damodaran Bahulayan、Litka John、Malathy Lalithambika

  DOI：10.1081/scc-120016343

  日期：2003.1.4

  Diazotization and diazocoupling reactions of aniline and its substituted derivatives with phenol and other aromatic amines over ecofriendly clay catalysts is described. This inexpensive, noncorrosive and reusable catalysts were found to exhibit bifunctional catalytic properties for these reactions. No considerable decrease in the efficiency of the catalysts were observed after five cycles of operation. The new method totally avoids the use of acids and alkalies.