N-ethyl-N-(propan-2-ylsulfanylmethyl)ethanamine | 6631-70-5

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫半缩醛胺衍生物
• 英文名称: N-ethyl-N-(propan-2-ylsulfanylmethyl)ethanamine
• 英文别名: diethyl-(isopropylsulfanyl-methyl)-amine；Diaethylaminomethyl-isopropyl-sulfid；Diaethyl-(isopropylmercapto-methyl)-amin；n-Ethyl-n-[(propan-2-ylsulfanyl)methyl]ethanamine
• CAS: 6631-70-5
• 化学式: C₈H₁₉NS
• 分子量: 161.312
• InChiKey: MZUBSHOGWXUPDT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  28.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  N,N,N',N'-四乙基甲二胺 、 异丙硫醇 在 samarium(III) chloride hexahydrate 作用下， 反应 6.0h， 以47%的产率得到N-ethyl-N-(propan-2-ylsulfanylmethyl)ethanamine
  参考文献：
  名称：

  Synthesis of amino sulfides in the presence of rare-earth and transition metal catalysts

  摘要：

  Efficient procedures have been developed for the synthesis of amino sulfides by aminomethylation of thiols with higher geminal diamines, thiomethylation of secondary amines with N,N-dimethylaminomethyl sulfides, and decyclization of 1,3,6-oxadithiepane or N-tert-butyl-1,5,3-dithiazepane with secondary amines in the presence of rare-earth and transition metals.

  DOI：

  10.1134/s1070428012070020

文献信息

• McLeod; Robinson, Journal of the Chemical Society, 1921, vol. 119, # 1471, p. 1474
  作者：McLeod、Robinson

  DOI：——

  日期：——
• Synthesis of amino sulfides in the presence of rare-earth and transition metal catalysts
  作者：R. R. Khairullina、B. F. Akmanov、R. V. Kunakova、A. G. Ibragimov

  DOI：10.1134/s1070428012070020

  日期：2012.7

  Efficient procedures have been developed for the synthesis of amino sulfides by aminomethylation of thiols with higher geminal diamines, thiomethylation of secondary amines with N,N-dimethylaminomethyl sulfides, and decyclization of 1,3,6-oxadithiepane or N-tert-butyl-1,5,3-dithiazepane with secondary amines in the presence of rare-earth and transition metals.