4H-Pyrrolo[2,3-d]thiazole-5-carboxamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯并噻唑
• 英文名称: 4H-Pyrrolo[2,3-d]thiazole-5-carboxamide
• 英文别名: 4H-pyrrolo[2,3-d][1,3]thiazole-5-carboxamide
• 化学式: C₆H₅N₃OS
• 分子量: 167.19
• InChiKey: GSTDLFUESDSNLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  100
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• THIAZOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS
  申请人：THE GLOBAL ALLIANCE FOR TB DRUG DEVELOPMENT, INC.

  公开号：US20220396586A1

  公开（公告）日：2022-12-15

  Provided herein are compounds of Formula (I) and Formula (II) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.
• [EN] THIAZOLE CARBOXAMIDE COMPOUNDS AND USE THEREOF FOR THE TREATMENT OF MYCOBACTERIAL INFECTIONS<br/>[FR] COMPOSÉS DE THIAZOLE CARBOXAMIDE ET LEUR UTILISATION POUR LE TRAITEMENT D'INFECTIONS MYCOBACTÉRIENNES
  申请人：THE GLOBAL ALLIANCE FOR TB DRUG DEV INC

  公开号：WO2021062318A1

  公开（公告）日：2021-04-01

  Provided herein are compounds of Formula (I) and Formula (II) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of tuberculosis.