1,3-dihydroxypropan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 内源性大麻素
• 英文名称: 1,3-dihydroxypropan-2-yl (5E,8E,11E,14E)-icosa-5,8,11,14-tetraenoate
• 化学式: C₂₃H₃₈O₄
• 分子量: 378.5
• InChiKey: RCRCTBLIHCHWDZ-CGRWFSSPSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  27
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.61
• 拓扑面积：
  66.8
• 氢给体数：
  2
• 氢受体数：
  4

文献信息

• Use of CBx cannabinoid receptor modulators as potassium channel modulators
  申请人：Antel Jochen

  公开号：US20070254863A1

  公开（公告）日：2007-11-01

  Methods of treating one or more medical conditions by administering to a subject in need thereof an effective amount of a CB x modulator having K ATP channel modulating properties are described herein. Also described are methods of using a CB x modulator having K ATP channel modulating properties to treat one or more medical conditions.
• Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators
  申请人：Antel Jochen

  公开号：US20070254862A1

  公开（公告）日：2007-11-01

  Described herein are pharmaceutical compositions comprising therapeutically effective quantities of (i) a K ATP channel modulator; and (ii) a CB x modulator. Also described herein are methods of making and using these compositions.
• US7763607B2
  申请人：——

  公开号：US7763607B2

  公开（公告）日：2010-07-27