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    —— (9aS)-2-[2-(1,3-benzodioxol-5-yloxy)acetyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C16H17N3O6
    (9aS)-2-[2-(1,3-benzodioxol-5-yloxy)acetyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-N-[4-(dimethylamino)phenyl]-8-methyl-9-oxo-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazine-2-carboxamide —— C17H25N5O2
    (9aR)-N-[4-(dimethylamino)phenyl]-8-methyl-9-oxo-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazine-2-carboxamide
    —— (9aS)-2-[[4-(2-methylpropyl)phenyl]methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C18H25N3O2
    (9aS)-2-[[4-(2-methylpropyl)phenyl]methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[(2-phenylimidazo[1,2-a]pyrimidin-3-yl)methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C20H22N6O
    (9aS)-2-[(2-phenylimidazo[1,2-a]pyrimidin-3-yl)methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-8-methyl-2-[2-(1,2,4-triazol-1-yl)acetyl]-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one —— C12H18N6O2
    (9aR)-8-methyl-2-[2-(1,2,4-triazol-1-yl)acetyl]-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-[(3-acetyl-2,4,6-trimethylphenyl)methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C19H27N3O2
    (9aS)-2-[(3-acetyl-2,4,6-trimethylphenyl)methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-(8-fluoroquinoline-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H15FN4O3
    (9aS)-2-(8-fluoroquinoline-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[2-(2-ethylimidazol-1-yl)acetyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C14H21N5O2
    (9aS)-2-[2-(2-ethylimidazol-1-yl)acetyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-8-methyl-2-[2-(1,2,4-triazol-1-yl)acetyl]-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one —— C12H18N6O2
    (9aS)-8-methyl-2-[2-(1,2,4-triazol-1-yl)acetyl]-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-2-(2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C14H17N3O4S
    (9aR)-2-(2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-(6-methylpyridazin-3-yl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C12H17N5O
    (9aS)-2-(6-methylpyridazin-3-yl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-8-methyl-2-(6-oxo-1H-pyridine-2-carbonyl)-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one —— C14H18N4O3
    (9aR)-8-methyl-2-(6-oxo-1H-pyridine-2-carbonyl)-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-2-[3-(2-methylindol-1-yl)propanoyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C19H24N4O2
    (9aR)-2-[3-(2-methylindol-1-yl)propanoyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9R)-9-(5-fluoro-2-pyrazol-1-ylphenyl)-1,6,8,9-tetrahydropyrido[3,2-g][1,4]benzoxazine-2,7-dione —— C20H15FN4O3
    (9R)-9-(5-fluoro-2-pyrazol-1-ylphenyl)-1,6,8,9-tetrahydropyrido[3,2-g][1,4]benzoxazine-2,7-dione
    —— (9R)-4-methyl-9-(2-phenylpyrazol-3-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione —— C21H18N4O3
    (9R)-4-methyl-9-(2-phenylpyrazol-3-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione
    —— (9aR)-2-[(3-hydroxy-6-methylpyridin-2-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C14H18N4O3
    (9aR)-2-[(3-hydroxy-6-methylpyridin-2-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9S)-4-methyl-9-(2-phenylpyrazol-3-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione —— C21H18N4O3
    (9S)-4-methyl-9-(2-phenylpyrazol-3-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione
    —— (9aR)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H21N3O3S
    (9aR)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H21N3O3S
    (9aS)-2-(5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophene-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-8-methyl-2-(1,3,5-trimethylpyrazol-4-yl)sulfonyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C14H21N5O4S
    (9aS)-8-methyl-2-(1,3,5-trimethylpyrazol-4-yl)sulfonyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[[2-(trifluoromethoxy)phenyl]methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C15H18F3N3O2
    (9aS)-2-[[2-(trifluoromethoxy)phenyl]methyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-[(3-hydroxy-6-methylpyridin-2-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C14H18N4O3
    (9aS)-2-[(3-hydroxy-6-methylpyridin-2-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-2-(8-fluoroquinoline-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H15FN4O3
    (9aR)-2-(8-fluoroquinoline-2-carbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-8-methyl-2-(6-oxo-1H-pyridine-2-carbonyl)-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one —— C14H18N4O3
    (9aS)-8-methyl-2-(6-oxo-1H-pyridine-2-carbonyl)-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-(2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C14H17N3O4S
    (9aS)-2-(2,3-dihydrothieno[3,4-b][1,4]dioxine-5-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H17FN4O2S
    (9aS)-2-[[4-(4-fluorophenyl)-1,3-thiazol-2-yl]methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-2-[2-(2-ethylimidazol-1-yl)acetyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C14H21N5O2
    (9aR)-2-[2-(2-ethylimidazol-1-yl)acetyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9S)-9-(5-fluoro-2-pyrazol-1-ylphenyl)-1,6,8,9-tetrahydropyrido[3,2-g][1,4]benzoxazine-2,7-dione —— C20H15FN4O3
    (9S)-9-(5-fluoro-2-pyrazol-1-ylphenyl)-1,6,8,9-tetrahydropyrido[3,2-g][1,4]benzoxazine-2,7-dione
    —— (9aR)-2-(3,5-dimethyl-1-benzofuran-2-carbonyl)-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C19H21N3O4
    (9aR)-2-(3,5-dimethyl-1-benzofuran-2-carbonyl)-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-2-[(2-ethyl-5-methyl-1H-imidazol-4-yl)methyl]-8-methyl-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazine —— C15H27N5
    (9aR)-2-[(2-ethyl-5-methyl-1H-imidazol-4-yl)methyl]-8-methyl-3,4,6,7,9,9a-hexahydro-1H-pyrazino[1,2-a]pyrazine
    —— (9R)-1-methyl-9-(6-phenoxypyridin-3-yl)-8,9-dihydro-6H-pyrido[3,2-g][1,4]benzoxazine-2,7-dione —— C23H19N3O4
    (9R)-1-methyl-9-(6-phenoxypyridin-3-yl)-8,9-dihydro-6H-pyrido[3,2-g][1,4]benzoxazine-2,7-dione
    —— (9S)-1-methyl-9-(6-phenoxypyridin-3-yl)-8,9-dihydro-6H-pyrido[3,2-g][1,4]benzoxazine-2,7-dione —— C23H19N3O4
    (9S)-1-methyl-9-(6-phenoxypyridin-3-yl)-8,9-dihydro-6H-pyrido[3,2-g][1,4]benzoxazine-2,7-dione
    —— (9R)-4-methyl-9-(3-propan-2-yl-1,2-oxazol-5-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione —— C18H19N3O4
    (9R)-4-methyl-9-(3-propan-2-yl-1,2-oxazol-5-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione
    —— (9aR)-2-[[3-(hydroxymethyl)-4-propan-2-yloxyphenyl]methyl]-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C19H27N3O4
    (9aR)-2-[[3-(hydroxymethyl)-4-propan-2-yloxyphenyl]methyl]-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-(3,5-dimethyl-1-benzofuran-2-carbonyl)-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C19H21N3O4
    (9aS)-2-(3,5-dimethyl-1-benzofuran-2-carbonyl)-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-2-[(6-chloro-2H-chromen-3-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H18ClN3O3
    (9aR)-2-[(6-chloro-2H-chromen-3-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[(6-chloro-2H-chromen-3-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C17H18ClN3O3
    (9aS)-2-[(6-chloro-2H-chromen-3-yl)methyl]-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C16H20N4O4S
    (9aS)-2-[(2-oxo-3,4-dihydro-1H-quinolin-6-yl)sulfonyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-[[3-(hydroxymethyl)-4-propan-2-yloxyphenyl]methyl]-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C19H27N3O4
    (9aS)-2-[[3-(hydroxymethyl)-4-propan-2-yloxyphenyl]methyl]-8-methyl-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9S)-4-methyl-9-(3-propan-2-yl-1,2-oxazol-5-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione —— C18H19N3O4
    (9S)-4-methyl-9-(3-propan-2-yl-1,2-oxazol-5-yl)-8,9-dihydro-6H-pyrido[2,3-g][1,4]benzoxazine-3,7-dione
    —— (9aS)-2-(2-benzyl-1,3-thiazole-4-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C18H20N4O2S
    (9aS)-2-(2-benzyl-1,3-thiazole-4-carbonyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-2-(1-methylpyrazolo[3,4-d]pyrimidin-4-yl)-1,3,4,5,7,8,9,9a-octahydropyrrolo[1,2-a][1,4]diazepine —— C14H20N6
    (9aR)-2-(1-methylpyrazolo[3,4-d]pyrimidin-4-yl)-1,3,4,5,7,8,9,9a-octahydropyrrolo[1,2-a][1,4]diazepine
    —— (9aS)-2-[3-(2,4-difluorophenyl)propanoyl]-8-methyl-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one —— C17H21F2N3O2
    (9aS)-2-[3-(2,4-difluorophenyl)propanoyl]-8-methyl-1,3,4,6,7,9a-hexahydropyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-2-(1-phenylcyclopentanecarbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C19H23N3O3
    (9aS)-2-(1-phenylcyclopentanecarbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-8-methyl-2-[[5-(pyrrolidin-1-ylmethyl)thiophen-2-yl]methyl]-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C18H26N4O2S
    (9aR)-8-methyl-2-[[5-(pyrrolidin-1-ylmethyl)thiophen-2-yl]methyl]-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-[1-(thiophene-2-carbonyl)piperidin-4-yl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C17H24N4O2S
    (9aS)-2-[1-(thiophene-2-carbonyl)piperidin-4-yl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aR)-2-(1-phenylcyclopentanecarbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione —— C19H23N3O3
    (9aR)-2-(1-phenylcyclopentanecarbonyl)-1,3,4,7,8,9a-hexahydropyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aR)-2-[2-methyl-3-(pyridin-3-ylmethylamino)benzoyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C21H25N5O2
    (9aR)-2-[2-methyl-3-(pyridin-3-ylmethylamino)benzoyl]-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one
    —— (9aS)-8-methyl-2-[[5-(pyrrolidin-1-ylmethyl)thiophen-2-yl]methyl]-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione —— C18H26N4O2S
    (9aS)-8-methyl-2-[[5-(pyrrolidin-1-ylmethyl)thiophen-2-yl]methyl]-3,4,7,9a-tetrahydro-1H-pyrazino[1,2-a]pyrazine-6,9-dione
    —— (9aS)-2-(4-pyrazol-1-ylbenzoyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one —— C17H19N5O2
    (9aS)-2-(4-pyrazol-1-ylbenzoyl)-3,4,6,7,8,9a-hexahydro-1H-pyrazino[1,2-a]pyrazin-9-one