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    —— (6E)-6-[[3-chloro-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C21H16ClN5O6S2
    (6E)-6-[[3-chloro-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— 6-chloro-N-[4-(methylsulfamoyl)phenyl]pyridine-3-carboxamide —— C13H12ClN3O3S
    6-chloro-N-[4-(methylsulfamoyl)phenyl]pyridine-3-carboxamide
    —— (6E)-6-[[4-[3-(2,6-dimethylphenoxy)propoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O5S2
    (6E)-6-[[4-[3-(2,6-dimethylphenoxy)propoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(3,4-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H23ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(3,4-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-(1,3-benzodioxol-5-ylmethoxy)phenyl]methylidene]-5-imino-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H22N4O6S2
    (6E)-6-[[4-(1,3-benzodioxol-5-ylmethoxy)phenyl]methylidene]-5-imino-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(2-ethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H23ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(2-ethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[3-methoxy-4-[(2-methylphenyl)methoxy]phenyl]methylidene]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O5S2
    (6E)-5-imino-6-[[3-methoxy-4-[(2-methylphenyl)methoxy]phenyl]methylidene]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(3,5-dimethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(3,5-dimethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[5-(4-bromophenyl)furan-2-yl]methylidene]-5-imino-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C20H17BrN4O4S2
    (6E)-6-[[5-(4-bromophenyl)furan-2-yl]methylidene]-5-imino-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[3-(4-methylphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[3-(4-methylphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(3,5-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H23ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(3,5-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— 6-chloro-N-[4-[methyl(propan-2-yl)sulfamoyl]phenyl]pyridine-3-carboxamide —— C16H18ClN3O3S
    6-chloro-N-[4-[methyl(propan-2-yl)sulfamoyl]phenyl]pyridine-3-carboxamide
    —— (6E)-5-imino-6-[[3-methoxy-4-[2-(3-methylphenoxy)ethoxy]phenyl]methylidene]-3-propan-2-ylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-5-imino-6-[[3-methoxy-4-[2-(3-methylphenoxy)ethoxy]phenyl]methylidene]-3-propan-2-ylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-ethoxy-4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21N5O7S2
    (6E)-6-[[3-ethoxy-4-[(4-nitrophenyl)methoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-ethoxy-4-(3-phenoxypropoxy)phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-6-[[3-ethoxy-4-(3-phenoxypropoxy)phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[4-[2-(2-methylphenoxy)ethoxy]phenyl]methylidene]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O5S2
    (6E)-5-imino-6-[[4-[2-(2-methylphenoxy)ethoxy]phenyl]methylidene]-3-(2-methylpropylsulfonyl)-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[(3-bromo-4-phenylmethoxyphenyl)methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C20H15BrN4O4S2
    (6E)-6-[(3-bromo-4-phenylmethoxyphenyl)methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(4-ethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(4-ethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[4-[3-(2-methoxyphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O6S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[4-[3-(2-methoxyphenoxy)propoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[(3,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C21H16Cl2N4O5S2
    (6E)-6-[[4-[(3,4-dichlorophenyl)methoxy]-3-methoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O6S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[2-(4-methylphenoxy)ethoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[2-(3-methylphenoxy)ethoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O6S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[2-(3-methylphenoxy)ethoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(2-prop-2-enylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H21ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(2-prop-2-enylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[1-[3-(4-methoxyphenoxy)propyl]indol-3-yl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H23N5O5S2
    (6E)-5-imino-6-[[1-[3-(4-methoxyphenoxy)propyl]indol-3-yl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(2-methoxy-4-methylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O6S2
    (6E)-6-[[3-chloro-4-[2-(2-methoxy-4-methylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[1-[3-(2-methoxyphenoxy)propyl]indol-3-yl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H23N5O5S2
    (6E)-5-imino-6-[[1-[3-(2-methoxyphenoxy)propyl]indol-3-yl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(2-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C22H19ClN4O6S2
    (6E)-6-[[3-chloro-4-[2-(2-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[3-(3,4-dimethylphenoxy)propoxy]-3-methoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-6-[[4-[3-(3,4-dimethylphenoxy)propoxy]-3-methoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[(2-fluorophenyl)methoxy]-3-methoxy-5-prop-2-enylphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H21FN4O5S2
    (6E)-6-[[4-[(2-fluorophenyl)methoxy]-3-methoxy-5-prop-2-enylphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-5-methoxy-4-(3-phenoxypropoxy)phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O6S2
    (6E)-6-[[3-chloro-5-methoxy-4-(3-phenoxypropoxy)phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-ethoxy-4-[2-(4-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O7S2
    (6E)-6-[[3-ethoxy-4-[2-(4-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(3,4-dimethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(3,4-dimethylphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-bromo-4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C20H14BrFN4O4S2
    (6E)-6-[[3-bromo-4-[(2-fluorophenyl)methoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[3-methoxy-4-[3-(4-methylphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O6S2
    (6E)-5-imino-6-[[3-methoxy-4-[3-(4-methylphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[3-(4-chlorophenoxy)propoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[4-[3-(4-chlorophenoxy)propoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[3-methoxy-4-[3-(3-methoxyphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O7S2
    (6E)-5-imino-6-[[3-methoxy-4-[3-(3-methoxyphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(2,6-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H23ClN4O5S2
    (6E)-6-[[3-chloro-4-[2-(2,6-dimethylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[2-(2,5-dimethylphenoxy)ethoxy]-3-ethoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-6-[[4-[2-(2,5-dimethylphenoxy)ethoxy]-3-ethoxyphenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[2-(4-chloro-3-methylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[[4-[2-(4-chloro-3-methylphenoxy)ethoxy]phenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C20H14ClN5O6S2
    (6E)-6-[[3-chloro-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[1-(1,3-benzodioxol-5-ylmethyl)-2-methylindol-3-yl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H21N5O5S2
    (6E)-6-[[1-(1,3-benzodioxol-5-ylmethyl)-2-methylindol-3-yl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-5-imino-6-[[3-methoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C24H24N4O6S2
    (6E)-5-imino-6-[[3-methoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[3-chloro-4-[2-(4-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C22H19ClN4O6S2
    (6E)-6-[[3-chloro-4-[2-(4-methoxyphenoxy)ethoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— 6-chloro-N-[4-(propan-2-ylsulfamoyl)phenyl]pyridine-3-carboxamide —— C15H16ClN3O3S
    6-chloro-N-[4-(propan-2-ylsulfamoyl)phenyl]pyridine-3-carboxamide
    —— (6E)-6-[[3-ethoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-6-[[3-ethoxy-4-[3-(3-methylphenoxy)propoxy]phenyl]methylidene]-5-imino-3-methylsulfonyl-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[(3-chloro-5-ethoxy-4-phenylmethoxyphenyl)methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C23H21ClN4O5S2
    (6E)-6-[(3-chloro-5-ethoxy-4-phenylmethoxyphenyl)methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C22H19N5O7S2
    (6E)-3-ethylsulfonyl-5-imino-6-[[3-methoxy-4-[(2-nitrophenyl)methoxy]phenyl]methylidene]-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one
    —— (6E)-6-[[4-[2-(3,5-dimethylphenoxy)ethoxy]-3-methoxyphenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one —— C25H26N4O6S2
    (6E)-6-[[4-[2-(3,5-dimethylphenoxy)ethoxy]-3-methoxyphenyl]methylidene]-3-ethylsulfonyl-5-imino-[1,2,4]thiadiazolo[4,5-a]pyrimidin-7-one