1-phosphatricyclo<3.3.1.1^3,7>decane | 90207-69-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 磷环化合物
• 英文名称: 1-phosphatricyclo<3.3.1.1^3,7>decane
• 英文别名: 2-Phosphatricyclo[3.3.1.13,7]decane
• CAS: 90207-69-5
• 化学式: C₉H₁₅P
• 分子量: 154.192
• InChiKey: DJXHXILQRDQZGU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  溴甲苯 、 1-phosphatricyclo<3.3.1.1^3,7>decane 以 氘代苯 为溶剂， 反应 2.0h， 以24%的产率得到1-benzyl-1-phosphoniatricyclo<3.3.1.1^3,7>decane bromide
  参考文献：
  名称：

  Synthesis of 1-phosphaadamantane

  摘要：

  DOI：

  10.1016/s0040-4020(01)88644-0
• 作为产物：
  描述：

  7-hydroxymethyl-3-phosphabicyclo<3.3.1>nonane 3-oxides 在 三氯硅烷 、 sodium 、 potassium iodide 作用下， 以 甲苯 为溶剂， 反应 4.0h， 生成 1-phosphatricyclo<3.3.1.1^3,7>decane
  参考文献：
  名称：

  Synthesis of 1-phosphaadamantane

  摘要：

  DOI：

  10.1016/s0040-4020(01)88644-0

文献信息

• [EN] PROCESS OF PREPARING GLYCOLALDEHYDE<br/>[FR] PROCEDE DE PREPARATION DE GLYCOLALDEHYDE
  申请人：SHELL INT RESEARCH

  公开号：WO2005058788A1

  公开（公告）日：2005-06-30

  The invention provides a process of preparing glycolaldehyde by reacting formaldehyde with hydrogen and carbon monoxide in the presence of a catalyst composition which is based on, a) a source of rhodium, and b) a ligand of general formula R1P-R2(I), wherein R1 is a bivalent radical that together with the phosphorous atom to which it is attached is an optionally substituted 2-phospha-tricyclo[3.3.1.13,7}]-decyl group, wherein from 1 to 5 of the carbon atoms has been replaced by a heteroatom, and wherein R2 is a monovalent radical which is an optionally substituted hydrocarbyl group having from 1 to 40 carbon atoms; a catalyst composition of use in said process; and a process of preparing ethylene glycol from the glycolaldehyde thus prepared.

  该发明提供了一种制备甘醛的方法，通过在催化剂组合物的存在下，将甲醛与氢气和一氧化碳反应，所述催化剂组合物基于a)铑的来源，和b)一般式R1P-R2(I)的配体，其中R1是一个二价基团，与其连接的磷原子一起是一个可选择替代的2-磷杂-三环[3.3.1.13,7}]-癸基团，其中1到5个碳原子已被杂原子取代，而R2是一个单价基团，是一个可选择替代的碳氢基团，含有1到40个碳原子；用于该方法的催化剂组合物；以及从制备的甘醛制备乙二醇的方法。
• [EN] PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE<br/>[FR] PROCEDE PERMETTANT LA CARBONYLATION D'UN DIENE CONJUGUE
  申请人：SHELL INT RESEARCH

  公开号：WO2004103948A1

  公开（公告）日：2004-12-02

  A process for the carbonylation of a conjugated diene, comprising reacting the conjugated diene with carbon monoxide and a co-reactant having a mobile hydrogen atom in the presence of a catalyst system including: (a) a source of palladium; and (b) a bidentate diphosphine ligand of formula (II): R1R2 > p1R3m-R-R4n-p2 < R5R6 wherein p1 and p2 represent phosphorus atoms; R1, R2, R5, and R6 independently represent the same or different optionally substituted organic radical containing a tertiary carbon atom through which each radical is linked to the phosphorus atom; R3 and R4 independently represent the same or different optionally substituted methylene groups; R represents an organic group comprising the bivalent bridging group C1-C2 through which R is connected to R3 and R4; m and n independently represent a natural number in the range of from 0 to 4, wherein the rotation about the bond between the carbon atoms C1 and C2 of the bridging group is restricted a temperature in the range of from 0 °C to 250 °C, and wherein the dihedral angle between the plane occupied by the three atom sequence composed of C1, C2 and the atom directly bonded to C1 in the direction of p1, and the plane occupied by the three atom sequence C1, C2 and the atom directly bonded to C2 in the direction of p2, is in the range of from 0 to 120°; and (c) a source of an anion.

  一种用于共轭二烯的羰基化过程，包括在催化剂系统的存在下将共轭二烯与一氧化碳和具有可移动氢原子的共反应剂反应，所述催化剂系统包括：(a) 钯源；和(b) 公式(II)的双膦双齿配体：R1R2 > p1R3m-R-R4n-p2 < R5R6，其中p1和p2代表磷原子；R1、R2、R5和R6独立地代表相同或不同的可选择取代的含有第三级碳原子的有机基团，每个基团通过其与磷原子的连接而与磷原子连接；R3和R4独立地代表相同或不同的可选择取代的亚甲基基团；R代表包含双价桥接基团C1-C2的有机基团，通过该基团R连接到R3和R4；m和n独立地代表在0到4范围内的自然数，其中在桥接基团的碳原子C1和C2之间的键的旋转受到限制；在0°C至250°C范围内的温度下进行；且在由C1、C2和直接与C1朝向p1方向上键合的原子组成的三原子序列所占据的平面和由C1、C2和直接与C2朝向p2方向上键合的原子组成的三原子序列所占据的平面之间的二面角在0到120°的范围内；和(c) 阴离子源。
• [EN] A CONTINUOUS PROCESS FOR THE CARBONYLATION OF ETHYLENE<br/>[FR] PROCÉDÉ CONTINU DE CARBONYLATION DE L'ÉTHYLÈNE
  申请人：LUCITE INT UK LTD

  公开号：WO2011073655A1

  公开（公告）日：2011-06-23

  A continuous process for carbonylation of ethylene in a liquid phase using carbon monoxide, a co-reactant and a suitable catalyst system is described. The process comprises the steps of: (i) forming a liquid phase comprising the co-reactant and a suitable catalyst system obtainable by combining: (a) a group VIII metal/compound; (b) a ligand of general formula (I) and c) optionally, a source of anions; wherein Q1 is optionally phosphorous; (ii) forming a gaseous phase in contact with the liquid phase by providing at least an ethylene gas input feed stream and a carbon monoxide gas input feed stream wherein the ethylene:CO molar ratio entering the liquid phase from the input feed streams is greater than 2:1; (iii) reacting ethylene with carbon monoxide in the presence of the co-reactant, and of the suitable catalyst system in the liquid phase; wherein the ethylene:CO gas molar ratio in the gaseous phase is between 20:1 and 1000:1 or wherein the molar ratio of ethylene:CO in the liquid phase is greater than 10:1.

  描述了一种在液相中使用一氧化碳、共同反应剂和适当的催化剂体系对乙烯进行羰基化的连续过程。该过程包括以下步骤：(i)形成包括共同反应剂和适当催化剂体系的液相，所述催化剂体系可通过组合获得：(a) VIII族金属/化合物；(b) 一般式(I)的配体和(c) 可选地，阴离子源；其中Q1可选为磷；(ii)通过提供至少一个乙烯气体输入流和一个一氧化碳气体输入流形成与液相接触的气相，在其中从输入流中进入液相的乙烯：CO摩尔比大于2:1；(iii)在液相中的共同反应剂和适当的催化剂体系的存在下，将乙烯与一氧化碳反应；其中气相中的乙烯：CO气体摩尔比在20:1至1000:1之间，或液相中的乙烯：CO摩尔比大于10:1。
• [EN] PROCESS FOR THE CARBONYLATION OF A CONJUGATED DIENE<br/>[FR] PROCEDE DE CARBONYLATION D'UN DIENE CONJUGUE
  申请人：SHELL INT RESEARCH

  公开号：WO2005082829A1

  公开（公告）日：2005-09-09

  A process for the carbonylation of a conjugated diene, comprising reacting the conjugated diene with carbon monoxide and a co-reactant having an active hydrogen atom in the presence of a catalyst system including: (a) a source of palladium; and (b) a bidentate diphosphine ligand of formula (II): R1 > P1 -R- P2 < R2R3 wherein P1 and p2 represent phosphorus atoms; R1 represents an optionally substituted divalent organic group linked to the phosphorus atom by two tertiary carbon atoms; and R2 and R3 independently represent univalent groups of from 1 to 20 atoms containing a tertiary carbon atom through which each group is linked to the phosphorus atom, or R2 and R3 jointly form an optionally substituted divalent organic group containing at least 2 tertiary carbon atoms through which the group is linked to the phosphorus atom; and R represents a divalent bridging group comprising 3 atoms through which P1 is linearly connected to P2;and (c) a source of an anion.

  一种共轭二烯的羰基化过程，包括在催化剂体系的存在下，将共轭二烯与一氧化碳和具有活性氢原子的共反应物反应，所述催化剂体系包括：（a）钯源；和（b）式（II）的双膦双齿配体：R1> P1-R-P2 磷原子的碳原子；R表示一个二价桥接基团，包括3个原子，通过该基团，P1线性连接到P2；和（c）一个阴离子源。
• [EN] BENZIMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND APPLICATION
  申请人：BRITISH BIO-TECHNOLOGY LIMITED

  公开号：WO1992003423A1

  公开（公告）日：1992-03-05

  (EN) Compounds of general formula (I) and their pharmaceutically and veterinarily acceptable acid addition salts and hydrates are antagonists of platelet activating factor (PAF) and as such are useful in the treatment or amelioration of various diseases or disorders mediated by PAF.(FR) Les composés répondant à la formule générale (I) et leurs hydrates et sels d'addition acide pharmaceutiquement et vétérinairement acceptables sont des antagonistes du facteur d'activation plaquettaire (PAF) et donc utiles au traitement ou à l'amélioration de diverses maladies ou troubles dus au PAF.

  通式（I）化合物及其药学和兽医可接受的酸加成盐和水合物是血小板活化因子（PAF）的拮抗剂，因此可用于治疗或改善由PAF介导的各种疾病或障碍。