磷酸钙粉末

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱土金属氧阴离子化合物
• 中文名称: 磷酸钙粉末
• 中文别名: 磷酸三钙；纤维素羟基磷灰石化合物；羟基磷灰石
• 英文名称: Pentacalcium tris(phosphate) hydroxide
• 英文别名: pentacalcium;hydroxide;triphosphate
• 化学式: Ca5HO13P3
• 分子量: 502.3
• InChiKey: XYJRXVWERLGGKC-UHFFFAOYSA-D

计算性质

• 辛醇/水分配系数(LogP)：
  -10.55
• 重原子数：
  21
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  260
• 氢给体数：
  1
• 氢受体数：
  13

反应信息

• 作为反应物：
  描述：

  磷酸钙粉末 生成 tricalcium;diphosphate
  参考文献：
  名称：

  SHIGERU, KEIJIRO;OKU, TAKASHI;TAKAGI, SHIGEHIDE, NIPPON SEHRAMIKKUSU KEKAJ GAKUDZYUTSU ROMBUNSYU, 97,(1989) N, S. 96-101

  摘要：

  DOI：
• 作为产物：
  描述：

  乙二醇 生成 磷酸钙粉末
  参考文献：
  名称：

  SIMODA, JOSIYUKI;OTI, YASUO

  摘要：

  DOI：
• 作为试剂：
  描述：

  无水氯化钙 、 disodium;hydrogen phosphate 、 氢氧化锂 在 磷酸钙粉末 作用下， 生成 磷酸钙粉末
  参考文献：
  名称：

  Process for producing hydroxylapatites

  摘要：

  提供了一种生产适用于生物高分子色谱分离的羟基磷灰石的方法。该方法包括在加热条件下，将六角柱状或针状的蒙脱石与氢氧化钾和/或氢氧化锂反应。

  公开号：

  US05073357A1

文献信息

• Ceramic forming process
  申请人：Sterling Drug Inc.

  公开号：US04312821A1

  公开（公告）日：1982-01-26

  A novel process is disclosed for producing a fracture-free shaped ceramic green body which comprises casting an aqueous suspension of hydroxylapatite, whitlockite or a mixture of these having a high water content and high drying shrinkage in an impervious mold, the cavity surfaces of which are coated with an inert water-immiscible lubricant; drying the casting under controlled conditions of temperature and humidity and removing adsorbed lubricant from the resulting dried green body.

  本发明公开了一种生产无裂陶瓷成型绿体的新工艺，其包括在不透水的模具中浇铸具有高含水量和高干燥收缩率的羟基磷灰石、白洛石或这两者的混合物的水性悬浮液，模具的腔面涂有惰性的不溶于水的润滑剂；在控制温度和湿度的条件下干燥铸造，并从所得的干燥绿体中去除吸附的润滑剂。
• Implant with bioactive particles stuck and method of manufacturing the same
  申请人：BRAINBASE CORPORATION

  公开号：US20020128723A1

  公开（公告）日：2002-09-12

  An implant includes a main body member having bio-compatibility, and particles formed ofbioactive material and dispersedly provided at the surface of an embedded section of the main body member. Each of the particles has a part embedded in the embedded portion and the other part protruding from the embedded portion. The main body member is formed of titanium or titanium alloy. The particles having osteo-conduction are formed of a material selected from among a group consisting of sintered substances of hydroxylapatite, &agr;-tricalcium phosphate, &bgr;-tricalcium phosphate, tetra-calcium phosphate, a single substance of amorphous calcium phosphate, monetite, brushite, 45S4 glass, and a mixture of them. It is desirable that the embedded section surface has a surface roughness in a range of 5 to 50 &mgr;m.

  该植入物包括一个具有生物相容性的主体成员，以及由生物活性材料形成的颗粒，分散地提供在主体成员的嵌入部分表面。每个颗粒都有一部分嵌入在嵌入部分中，另一部分突出于嵌入部分。主体成员由钛或钛合金制成。具有骨导性的颗粒由从羟基磷灰石、α-三钙磷酸盐、β-三钙磷酸盐、四钙磷酸盐、无定形磷酸钙单一物质、蒙脱石、磷酸钙和它们的混合物中选择的材料形成。最好嵌入部分表面具有5到50微米范围内的表面粗糙度。
• Process of preparing hydroxylapatite
  申请人：United States Gypsum Company

  公开号：US04849193A1

  公开（公告）日：1989-07-18

  This invention relates to the manufacture of hydroxylapatite in a through-solution process wherein monobasic calcium phosphate is reacted with a calcium hydroxide solution. In a preferred embodiment, an acidic premix is formed by reacting phosphoric acid and calcium hydroxide with high shear agitation in a first stage, and thereafter reacting the acidic premix with a saturated solution of calcium hydroxide also under high shear agitation in a second stage. The second stage reaction is carried out in an alkaline solution by carefully metering the acid premix into the calcium hydroxide solution whereby the pH of the solution is maintained above 11 until the reaction is near completion. It is particularly preferred to use a stoichiometric portion of calcium hydroxide in carrying out the reactions. After the hydroxylapatite precipitate is recovered, it may be sintered at a temperature between about 700.degree. C. and 1100.degree. C. for about 5 to 30 minutes to form a crystalline hydroxylapatite.

  本发明涉及通过溶液法制备羟基磷灰石的方法，其中单碱基磷酸钙与氢氧化钙溶液发生反应。在一种优选实施例中，首先在第一阶段中通过高剪切搅拌反应磷酸和氢氧化钙形成酸性预混料，然后在第二阶段中通过高剪切搅拌反应酸性预混料和饱和氢氧化钙溶液。第二阶段反应在碱性溶液中进行，通过仔细地将酸性预混料滴入氢氧化钙溶液中，使溶液的pH值保持在11以上，直到反应接近完成。在反应中特别优选使用化学计量量的氢氧化钙。在沉淀出羟基磷灰石后，可以将其烧结在700℃至1100℃的温度下，持续5至30分钟，形成晶体羟基磷灰石。
• Method for producing a suspension of hydroxylapatite
  申请人：Aktsionernoe Obschestvo Zakrytogo Tipa “Ostim”

  公开号：US06254855B1

  公开（公告）日：2001-07-03

  An improved hydroxylapatite HAP composition is in the form of a suspension or paste. The improvement is that the composition may have a homogenous concentration in the range of from 7% to 96%. The invention is also concerned with a method for producing the homogeneous concentration compositions of HAP and their industrial applications.

  一种改进的羟基磷灰石（HAP）组合物以悬浮液或糊状形式存在。改进之处在于，该组合物可以具有均匀浓度，范围在7%至96%之间。该发明还涉及一种制备HAP均匀浓度组合物的方法及其工业应用。
• Implant with bioactive particles stuck and method of manufacturing the
  申请人：Brainbase Corporation

  公开号：US05934287A1

  公开（公告）日：1999-08-10

  An implant includes a main body member having bio-compatibility, and particles formed of bioactive material and dispersedly provided at the surface of an embedded section of the main body member. Each of the particles has a part embedded in the embedded portion and the other part protruding from the embedded portion. The main body member is formed of titanium or titanium alloy. The particles having osteo-conduction are formed of a material selected from among a group consisting of sintered substances of hydroxylapatite, .alpha.-tricalcium phosphate, .beta.-tricalcium phosphate, tetra-calcium phosphate, a single substance of amorphous calcium phosphate, monetite, brushite, 45S4 glass, and a mixture of them. It is desirable that the embedded section surface has a surface roughness in a range of 5 to 50 .mu.m.

  一种植入物包括一个具有生物相容性的主体成员，以及由生物活性材料形成的颗粒，分散地提供在主体成员的嵌入部分的表面。每个颗粒都有一个嵌入在嵌入部分中的部分和从嵌入部分突出的另一部分。主体成员由钛或钛合金制成。具有骨导性的颗粒由从羟基磷灰石、α-三钙磷酸盐、β-三钙磷酸盐、四钙磷酸盐、无定形磷酸钙的单一物质，蒙脱石、磷酸二氢钙、45S4玻璃和它们的混合物中选择的材料形成。最好嵌入部分表面具有5到50微米范围内的表面粗糙度。