diethyl glycerol 3-phosphate | 1866-27-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: diethyl glycerol 3-phosphate
• 英文别名: 1-O-(diethoxyphosphoryl)-D,L-glycerol；2,3-Dihydroxy-1-propyl di-ethyl phosphate；2,3-dihydroxypropyl diethyl phosphate
• CAS: 1866-27-9
• 化学式: C₇H₁₇O₆P
• 分子量: 228.182
• InChiKey: MWQAWQSFGUKCKG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  85.2
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  diethyl glycerol 3-phosphate 、 十八烷酰氯 在 吡啶 作用下， 以 甲苯 为溶剂， 反应 6.0h， 以63%的产率得到diethyl 1,2-di-O-stearoyl-rac-glycerol 3-phosphate
  参考文献：
  名称：

  Smirnova, L.I.; Malenkovskaya, M. A.; Predvoditelev, D. A., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 1011 - 1019

  摘要：

  DOI：
• 作为产物：
  描述：

  1-O-(diethoxyphosphoryl)-2,3-O-isopropylidene-D,L-glycerol 以 水 为溶剂， 反应 1.0h， 以94%的产率得到diethyl glycerol 3-phosphate
  参考文献：
  名称：

  Autocleavage ofO-Isopropylidene ProtectedO-Phosphono- andO- Thionophosphono Esters of Sugars

  摘要：

  Phosphorylation of D-glucose, D-galactose, D-fructose, glycerol and xylitol acetals with diethoxy- or diphenoxy(thiono)phosphoryl chloride gave the corresponding esters. A novel method of partially and fully deprotecting these compounds, which we have called "autocatalytic cleavage", was effected by simply refluxing in water. Antifungal and insecticidal properties of these compounds are presented.

  DOI：

  10.1080/07328300008544073

文献信息

• SMIRNOVA L. I.; MALENKOVSKAYA M. A.; PREDVODITELEV D. A.; NIFANTEV EH. E., ZH. ORGAN. XIMII, 1980, 16, HO 6, 1170-1179
  作者：SMIRNOVA L. I.、 MALENKOVSKAYA M. A.、 PREDVODITELEV D. A.、 NIFANTEV EH. E.

  DOI：——

  日期：——
• NOVEL MULTIFUNCTIONAL MOLECULES FOR DENTAL BONDING APPLICATIONS HAVING IMPROVED ADHESION
  申请人：Septodont Confi-Dental Division

  公开号：EP2482787A2

  公开（公告）日：2012-08-08
• [EN] NOVEL MULTIFUNCTIONAL MOLECULES FOR DENTAL BONDING APPLICATIONS HAVING IMPROVED ADHESION<br/>[FR] NOUVELLES MOLÉCULES MULTIFONCTIONNELLES AYANT UNE ADHÉRENCE AMÉLIORÉE POUR APPLICATIONS DE COLLAGE DENTAIRE
  申请人：SEPTODONT CONFI DENTAL DIVISION

  公开号：WO2011041677A2

  公开（公告）日：2011-04-07

  The present invention describes dental adhesive compositions used for bonding dental biomaterials to hard tissue comprising a polymerizable blend of one or more newly synthesized low shrinkage, stable, multifunctional compounds, where the compounds are acidic-methacrylate derivatives, having excellent properties of bonding the hard tooth substance (enamel or dentin) to dental restorative materials, and present high quality marginal sealing between the tooth and the material thus bond and improved storage stability
• Autocleavage of<i>O</i>-Isopropylidene Protected<i>O</i>-Phosphono- and<i>O</i>- Thionophosphono Esters of Sugars
  作者：Denis Postel、Gino Ronco、Pierre Villa

  DOI：10.1080/07328300008544073

  日期：2000.1

  Phosphorylation of D-glucose, D-galactose, D-fructose, glycerol and xylitol acetals with diethoxy- or diphenoxy(thiono)phosphoryl chloride gave the corresponding esters. A novel method of partially and fully deprotecting these compounds, which we have called "autocatalytic cleavage", was effected by simply refluxing in water. Antifungal and insecticidal properties of these compounds are presented.
• Smirnova, L.I.; Malenkovskaya, M. A.; Predvoditelev, D. A., Journal of Organic Chemistry USSR (English Translation), 1980, vol. 16, p. 1011 - 1019
  作者：Smirnova, L.I.、Malenkovskaya, M. A.、Predvoditelev, D. A.、Nifant'ev, E. E.

  DOI：——

  日期：——