bis-(2-((ethylimino)methyl)-4-((4-flourophenyl)diazenyl)phenol)ethane-1,2-dithiol | 1616482-65-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: bis-(2-((ethylimino)methyl)-4-((4-flourophenyl)diazenyl)phenol)ethane-1,2-dithiol
• CAS: 1616482-65-5
• 化学式: C₃₂H₃₀F₂N₆O₂S₂
• 分子量: 632.758
• InChiKey: YXSOMYPFKPNUNI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.21
• 重原子数：
  44.0
• 可旋转键数：
  15.0
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  114.62
• 氢给体数：
  2.0
• 氢受体数：
  10.0

反应信息

• 作为产物：
  描述：

  1,8-二胺-3,6-二硫杂辛烷 、 1-(3-formyl-4-hydroxyphenylazo)-4-flourobenzene 以 乙醇 为溶剂， 反应 4.5h， 以78.79%的产率得到bis-(2-((ethylimino)methyl)-4-((4-flourophenyl)diazenyl)phenol)ethane-1,2-dithiol
  参考文献：
  名称：

  Solvatochromism, spectral properties and antimicrobial activities of new azo–azomethine dyes with N2S2O2 donor set of atoms

  摘要：

  Six new azo-azomethine dyes, H2Ln (n = 1-6), with N2S2O2 donor set of atoms have been prepared via condensation reaction of 1,10-diaza-4,7-dithiadecane, I, with substituted azo-coupled salicylaldehyde. The dyes were characterized by IR, UV-Vis and 1H NMR spectroscopic methods as well as elemental analysis. The solvatochromic behavior of the dyes was also probed by studying their UV-Vis spectra in four pure organic solvents of different polarities and a meaningful correlation was observed. Furthermore, all prepared dyes were assayed for their antibacterial and antifungal activities by disc diffusion method. The results indicated that all prepared dyes show good inhibition against Staphylococcus epidermidis and Bacillus cereus and did not show any antibacterial activity against Escherichia coli as compared to standard drugs. (C) 2014 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2014.05.014