cis-2,3-dimethyl-1-methoxyaziridine | 61593-25-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环丙烷
• 英文名称: cis-2,3-dimethyl-1-methoxyaziridine
• 英文别名: (2S,3R)-1-methoxy-2,3-dimethylaziridine
• CAS: 61593-25-7
• 化学式: C₅H₁₁NO
• 分子量: 101.148
• InChiKey: JOIYWHWGTCPMNL-XEAPYIEGSA-N

物化性质

• 沸点：
  80.9±23.0 °C(Predicted)
• 密度：
  0.94±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.64
• 重原子数：
  7.0
• 可旋转键数：
  1.0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  12.24
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为产物：
  描述：

  顺-2-丁烯 、 N,N-dimethoxyamine 在 三氟化硼乙醚 、 氨 作用下， 生成 cis-2,3-dimethyl-1-methoxyaziridine
  参考文献：
  名称：

  Electrophilically catalyzed splitting of dimethoxyamine to methoxynitrenium ion and its reactions

  摘要：

  The electrophilically catalyzed splitting of the N-O bond of dimethoxyamine results in the formation of methoxynitrenium ion, which in reaction with nucleophiles exhibits properties of an ambidentate cation - it methylates rigid nucleophiles and epiminates olefins. The stereospecificity of the addition of the nitrenium ion to cis-2-butene indicates its existence in a singlet electronic ground state.

  DOI：

  10.1007/bf00962392

文献信息

• Electrophilically catalyzed splitting of dimethoxyamine to methoxynitrenium ion and its reactions
  作者：V. F. Rudchenko、S. M. Ignatov、I. I. Chervin、A. �. Aliev、R. G. Kostyanovskii

  DOI：10.1007/bf00962392

  日期：1990.6

  The electrophilically catalyzed splitting of the N-O bond of dimethoxyamine results in the formation of methoxynitrenium ion, which in reaction with nucleophiles exhibits properties of an ambidentate cation - it methylates rigid nucleophiles and epiminates olefins. The stereospecificity of the addition of the nitrenium ion to cis-2-butene indicates its existence in a singlet electronic ground state.