碘化3,3-二乙基氧杂二羰花青 | 14806-50-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并恶唑啉
• 中文名称: 碘化3,3-二乙基氧杂二羰花青
• 中文别名: DODC碘化物；碘化-3,3ˊ-二乙基氧杂二羰花青；5-(3-乙基苯并恶唑-2-亚基)-1-(3-乙基苯并恶唑鎓-2-基)-1,3-戊二烯碘化物；3,3'-二乙基氧代二羰花青碘化物
• 英文名称: 3,3'-diethyloxadicarbocyanine iodide
• 英文别名: Dodci；5-(3-Ethylbenzoxazol-2-ylidene)-1-(3-ethylbenzoxazolium-2-yl)-1,3-pentadiene Iodide；(2Z)-3-ethyl-2-[5-(3-ethyl-1,3-benzoxazol-3-ium-2-yl)penta-2,4-dienylidene]-1,3-benzoxazole;iodide
• CAS: 14806-50-9；64173-98-4
• 化学式: C₂₃H₂₃N₂O₂*I
• 分子量: 486.352
• InChiKey: CLDZYSUDOQXJOU-UHFFFAOYSA-M

物化性质

• 熔点：
  232 °C (dec.)(lit.)
• 溶解度：
  在DMF中可溶

计算性质

• 辛醇/水分配系数(LogP)：
  2.07
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• TSCA：
  Yes
• 危险品标志：
  Xi
• 危险类别码：
  R36/37/38
• WGK Germany：
  3

反应信息

• 作为反应物：
  描述：

  碘化3,3-二乙基氧杂二羰花青 、 α-环糊精 以 水 为溶剂， 生成
  参考文献：
  名称：

  花青染料-环麦芽寡糖体系的物理化学方面：增强染料的二聚作用并缩短光异构体的寿命

  摘要：

  摘要环麦芽糖肽（βCD）和环麦芽八糖（γCD）增强了某些花青染料在水溶液中的二聚作用。增强的存在与否取决于连接链的长度，链上是否存在大原子以及在每个末端的发色团的大小。这些CD加速了某些花菁染料的光异构体对原始构象异构体的逆反应。光敏异构体的瞬态吸收显示出单指数衰减，表明CD腔中和溶液中的光敏异构体迅速平衡。对于具有增强的二聚作用的每个染料-CD对，光异构体的寿命缩短了，但并非总能获得相反的结果。光异构体寿命的缩短涉及CD腔中包含的单体染料。

  DOI：

  10.1016/0008-6215(89)85179-1
• 作为产物：
  描述：

  丙二酸 、 2-[2-(乙酰基苯基氨基)乙烯基]-3-乙基苯并恶唑鎓碘化物 在 三乙胺 作用下， 生成 碘化3,3-二乙基氧杂二羰花青
  参考文献：
  名称：

  160.在链上具有甲基作为取代基的对称二碳花菁

  摘要：

  DOI：

  10.1039/jr9450000595

文献信息

• IMAGING CONTRAST AGENTS USING NANOPARTICLES
  申请人：Zheng Shiying

  公开号：US20080095699A1

  公开（公告）日：2008-04-24

  The present invention relates to a nanoparticle comprising self-assembled crosslinked, amphiphilic block copolymers and at least one immobilized dye, wherein the self-assembled, crosslinked, amphiphilic block copolymers comprise a hydrophilic block and a hydrophobic block, wherein the self-assembled, crosslinked, amphiphilic block copolymers are self-assembled to form a core of the nanoparticle comprising a hydrophobic block, wherein the hydrophobic block is derived from at least one pendant multifunctional crosslinked alkoxy silane or amino silane moiety, and an exterior of the nanoparticle comprising a hydrophilic block, and wherein the immobilized dye is immobilized in the core.

  本发明涉及一种纳米颗粒，包括自组装交联的两性块共聚物和至少一种固定的染料，其中自组装交联的两性块共聚物包括一个亲水性块和一个疏水性块，其中自组装交联的两性块共聚物自组装形成纳米颗粒的核心，包括一个疏水性块，其中疏水性块源自至少一种挂链多功能交联的烷氧基硅烷或氨基硅烷基团，以及纳米颗粒的外部包括一个亲水性块，固定的染料固定在核心中。
• Loaded latex optical molecular imaging probes
  申请人：Leon Jeffrey W.

  公开号：US20080181965A1

  公开（公告）日：2008-07-31

  The present invention relates to a loaded latex particle comprising a latex material made from a mixture represented by formula (X)m-(Y)n-(Z)o-(W)p, wherein Y is at least one monomer with at least two ethylenically unsaturated chemical functionalities; Z is at least one polyethylene glycol macromonomer with an average molecular weight of between 300 and 10,000; W is an ethylenic monomer different from X, Y, or Z; and X is at least one water insoluble, alkoxethyl containing monomer; and m, n, o, and p are the respective weight percentages of each monomer. The particle may be loaded with a fluorescent dye.

  本发明涉及一种载荷乳胶颗粒，该乳胶材料由以下式表示的混合物制成：(X)m-(Y)n-(Z)o-(W)p，其中Y至少是一种具有至少两个乙烯不饱和化学官能团的单体；Z至少是一种聚乙二醇马克蒙单体，其平均分子量在300至10,000之间；W是与X、Y或Z不同的乙烯单体；X至少是一种水不溶性、含有烷氧基乙烯的单体；m、n、o和p分别是每种单体的重量百分比。该颗粒可以装载荧光染料。
• Cyanoborate, Fluoroalkylphosphate, Fluoroalkylborate or Imide Dyes
  申请人：Ignatyev Nikolai (Mykola)

  公开号：US20080275224A1

  公开（公告）日：2008-11-06

  The present invention relates to dyes of the general formula CAT + Y − (I), where Y − is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT + is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for colouring plastics and plastic fibres, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for colouring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.

  本发明涉及一般公式CAT+Y-（I）的染料，其中Y-是从氰硼酸盐、氟烷基磷酸盐、氟烷基硼酸盐或咪唑盐组中选择的阴离子，CAT+是从吖嗪、黄色素、聚甲烯、苯乙烯、偶氮、四唑、吡啶杂环、苯并吡喃杂环、硫吡喃杂环、苯并硫吡喃杂环、噻吩、噁吩、三芳基甲烷、二芳基甲烷、甲烯、花菁、喹啉、异喹啉或季铵氮杂花菁染料组中选择的阳离子，用于染色塑料和塑料纤维，用于制备凹版印刷油墨，作为圆珠笔浆料、邮票墨水，用于染色皮革和纸张，用于数据采集系统、复印、油墨微滤器、光电镀、激光技术和照相产业。
• CYANOBORATE, FLUOROALKYLPHOSPHATE, FLUOROALKYLBORATE OR IMIDE DYES
  申请人：IGNATYEV Nikolai (Mykola)

  公开号：US20110190480A1

  公开（公告）日：2011-08-04

  The present invention relates to dyes of the general formula CAT + Y − (I), where Y − is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT + is a cation selected from the group of the azine, xanthene, polymethine, styryl, azo, tetrazolium, pyrylium, benzopyrylium, thiopyrylium, benzothiopyrylium, thiazine, oxazine, triarylmethane, diarylmethane, methine, acridine, quinoline, isoquinoline or quaternary azafluorenone dyes, for colouring plastics and plastic fibres, for the preparation of flexographic printing inks, as ball-point pen pastes, as stamp ink, for colouring leather and paper, for use in data acquisition systems, reprography, in ink microfilters, in photogalvanics, laser technology and the photo industry.

  本发明涉及一般式CAT+Y−（I）的染料，其中Y−是从氰硼酸盐、氟烷基磷酸盐、氟烷基硼酸盐或咪唑盐群中选择的阴离子，CAT+是从偶氮、黄色素、聚甲烯、苯乙烯、偶氮、四唑、吡啶、苯并吡喃、硫吡喃、苯并硫吡喃、噻吩、噁唑、三芳基甲烷、二芳基甲烷、甲烷、吖啶、喹啉、异喹啉或季铵氮芴酮染料群中选择的阳离子，用于着色塑料和塑料纤维，制备柔性版印刷油墨，作为圆珠笔膏、邮票墨水，用于着色皮革和纸张，用于数据采集系统，复印术，墨水微滤器，光电镀技术，激光技术和光学工业。
• General method for the covalent immobilisation of indicators in, or onto a support useful for the fabrication of optical sensors
  申请人：Innosense S.r.l.

  公开号：EP1213583A1

  公开（公告）日：2002-06-12

  The invention discloses a method for the covalent immobilisation of indicator dyes in, or onto a support. The dyes can work in absorbance, reflectance or fluorescence mode. The dyed support is useful as the transducer element in an optical sensor. According to the invention, Figure 1, the indicator dye is dissolved or suspended in a solvent medium, optionally containing electrolytes to control ionic strength and pH. Aqueous formaldehyde is then added to the mixture. A support to be used as the sensing element in an optical sensor is added to the mixture and stirred or shaken for a period of time at a temperature comprised between room temperature and 100°C. Suitable supports include inorganic and organic polymers with primary and/or secondary amino groups.

  本发明公开了一种将指示剂染料共价固定在支持物中或支持物上的方法。这些染料可以在吸光、反射或荧光模式下工作。染色支撑物可用作光学传感器中的换能器元件。根据本发明，如图 1 所示，指示剂染料溶解或悬浮在溶剂介质中，可选择含有电解质以控制离子强度和 pH 值。然后向混合物中加入甲醛水溶液。将用作光学传感器传感元件的支撑物加入混合物中，并在室温至 100°C 之间的温度下搅拌或振荡一段时间。合适的支撑物包括带有伯氨基和/或仲氨基的无机和有机聚合物。

表征谱图