dipropyl phosphoramidate | 17123-09-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: dipropyl phosphoramidate
• 英文别名: Dipropylphosphoramidat；Phosphorsaeure-dipropylester-amid；Dipropyl-phosphorsaeureamid；Amidophosphorsaeure-di-n-propylester；phosphoramidic acid dipropyl ester；1-[Amino(propoxy)phosphoryl]oxypropane
• CAS: 17123-09-0
• 化学式: C₆H₁₆NO₃P
• 分子量: 181.172
• InChiKey: UAEJHSJCCBUAAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  61.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dipropyl phosphoramidate 在 sodium acetate 、 氯 作用下， 以 水 为溶剂， 生成 dichloro-phosphoramidic acid dipropyl ester
  参考文献：
  名称：

  Markovskii,L.N. et al., Journal of general chemistry of the USSR, 1970, vol. 40, p. 509 - 511

  摘要：

  DOI：
• 作为产物：
  描述：

  氯磷酸二正丙基酯 在 氨 作用下， 以 Petroleum ether 为溶剂， 生成 dipropyl phosphoramidate
  参考文献：
  名称：

  Meznik, Lubomir; Marecek, Ales, Zeitschrift fur Chemie, 1981, vol. 21, # 8, p. 294 - 295

  摘要：

  DOI：

文献信息

• N,N-Dihalophosphoramides—VI
  作者：S. Zawadzki、A. Zwierzak

  DOI：10.1016/s0040-4020(01)93296-x

  日期：1973.1

  O,O′-Dialkyl N,N-dibromophosphoroamidates, a novel pseudohalogen-type reagent has been prepared by direct bromination of O,O′-dialkyl phosphoroamidates in aqueous potassium carbonate. The preparative usefulness of these compounds in the synthesis of N-phosphorylated 2-phenylaziridines has been demonstrated.

  O，O′-二烷基N，N-二溴代磷酰胺基酸酯，通过在碳酸钾水溶液中直接溴化O，O′-二烷基磷酰胺基酯，制备了一种新型的假卤素型试剂。已经证明这些化合物在N-磷酸化的2-苯基氮丙啶的合成中的制备用途。
• An efficient and green method for the synthesis of<i>N</i>-phosphoramino<i>o</i>-hydroxylphenyl α-aminophosphonic monoesters
  作者：Jianfeng Zhang、Yadan Wang、Zhanwei Cui、Fei Wang、Zhiwei Miao、Ruyu Chen

  DOI：10.1002/hc.20483

  日期：2008.9

  An efficient and green method to the synthesis of N-protected o-hydroxylphenyl α-amino-alkylphosphonic monoesters is described. It consists of the three-component Mannich-type reaction of phosphoramides, carbonyl compounds (aldehydes or ketones), and 2-chlorobenzo[1,3,2] diox-aphospholes under solvent-free and catalyst-free conditions, followed by hydrolysis. © 2008 Wiley Periodicals, Inc. Heteroatom

  描述了一种合成 N-保护的邻羟基苯基α-氨基-烷基膦酸单酯的有效和绿色方法。它由磷酰胺、羰基化合物（醛或酮）和 2-氯苯并[1,3,2] 二氧杂磷在无溶剂和无催化剂条件下的三组分曼尼希型反应组成，然后水解。© 2008 Wiley Periodicals, Inc. 杂原子化学 19:596–601, 2008; 在线发表于 Wiley InterScience (www.interscience.wiley.com)。DOI 10.1002/hc.20483
• Lankacidin derivatives and production thereof
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP0226896A2

  公开（公告）日：1987-07-01

  The present invention provides lankacidin derivative [1] and production thereof. The lankacidin derivative [1] shows excellent anti- microbial activities and thus can be used for prophylaxis and treatment of infectious disease in animals.

  本发明提供了兰卡苷衍生物[1]及其生产方法。 兰卡苷衍生物[1]具有优异的抗微生物活性，因此可用于动物传染病的预防和治疗。
• Pyridine amides and their salts, processes for their production and pesticidal compositions containing them
  申请人：ISHIHARA SANGYO KAISHA, LTD.

  公开号：EP0580374A1

  公开（公告）日：1994-01-26

  The amide compound of the formula (I) or its salt: wherein X is an oxygen atom or a sulfur atom, Y is a haloalkyl group, each of R¹ and R² which are independent of each other, is a hydrogen atom, an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, a cycloalkyl group which may be substituted, -C(W¹)R³, -S(O)nR⁴ or -NHR⁵, or R¹ and R² together form =C(R⁶)R⁷ or together with the adjacent nitrogen atom form a C₄₋₅ 5- or 6-member heterocyclic group which may contain a nitrogen atom or an oxygen atom, R³ is an alkyl group which may be substituted, an alkenyl group which may be substituted, an alkynyl group which may be substituted, a cycloalkyl group which may be substituted, an aryl group which may be substituted, an alkoxy group, an alkylthio group or a mono- or di-alkylamino group, R⁴ is an alkyl group or a dialkylamino group, R⁵ is an alkyl group or an aryl group, each of R⁶ and R⁷ which are independent of each other, is an alkoxy group or an alkylthio group, W¹ is an oxygen atom or a sulfur atom, m is 0 or 1, and n is 1 or 2, provided that when m is 0 and X is an oxygen atom, R¹ and R² are not simultaneously hydrogen atoms.

  式 (I) 的酰胺化合物或其盐： 其中 X 是氧原子或硫原子，Y 是卤代烷基，相互独立的 R¹ 和 R² 分别是氢原子、可被取代的烷基、可被取代的烯基、可被取代的炔基、可被取代的环烷基、-C(W¹)R³、-S(O)nR⁴ 或 -NHR⁵，或 R¹ 和 R² 一起形成 =C(R⁶)R⁷，或与邻近的氮原子一起形成一个 C₄₋₅ 5 或 6 元杂环基团，该基团可包含一个氮原子或一个氧原子，R³ 是一个可被取代的烷基、R⁴ 是烷基或二烷基氨基、R⁵ 是烷基或芳基，相互独立的 R⁶ 和 R⁷ 各自是烷氧基或烷硫基，W¹ 是氧原子或硫原子，m 是 0 或 1，n 是 1 或 2，但当 m 是 0 且 X 是氧原子时，R¹ 和 R² 不同时是氢原子。
• Pudovik,A.N.; Krupnov,G.P., Journal of general chemistry of the USSR, 1963, vol. 33, p. 1612 - 1614
  作者：Pudovik,A.N.、Krupnov,G.P.

  DOI：——

  日期：——