sodium sulfite

• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱金属含氧阴离子化合物
• 英文名称: sodium sulfite
• 英文别名: Na2SO3；Sodium;sulfite
• 化学式: Na*O₃S
• 分子量: 103.054
• InChiKey: DWAQJAXMDSEUJJ-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  -4.0
• 重原子数：
  5
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  82.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,5-difluoro-α,α-dichloroacetophenone 、 sodium sulfite 在 盐酸 作用下， 以 sodium hypobromide 、 水 为溶剂， 生成 2,5-二氟苯甲酸
  参考文献：
  名称：

  Process for the preparation of fluorinated benzoic acids

  摘要：

  在制备化学式I的氟代苯甲酸过程中，其中X和Y，例如，彼此独立地表示氯或氟，而X还表示溴，化学式II的氟代氯代苯乙酮与次氯酸盐发生反应。

  公开号：

  US05093529A1
• 作为产物：
  描述：

  sodium sulfite 以 not given 为溶剂， 生成 sodium sulfite
  参考文献：
  名称：

  In Search of Covalently Bound Tetra- and Penta-Oxygen Species:  A Photoelectron Spectroscopic and Ab Initio Investigation of MO₄^- and MO₅^- (M = Li, Na, K, Cs)

  摘要：

  Although neutral and ionic O-4(0/-/+) Species have been observed experimentally and considered for energetic materials, O-4(2-) and O-5(2-) dianions have not yet been explored. O-4(2-) is valent isoelectronic to the well-known C\O-3(-) and SO32- anions, and O-5(2-) is valent isoelectronic to C\O-4(-) and SO42-. All are stable, common anions in solutions and inorganic salts. In this article, we explore the possibility of making covalenty bound O-4(2-) and O-5(2-) species stabilized in the forms Of M+O42- and M+O52- (M = Li, Na, K, Cs) in the gas phase. Laser vaporization experiments using M-containing targets and an O-2-seeded carrier gas yielded very intense mass peaks corresponding to MO4- and MO5-. To elucidate the structure and bonding of the newly observed MO4- and MO5- species, we measured their photoelectron spectra and then compared them with ab initio calculations and the spectra of C\O-3(-), Na+SO32-, C\O-4(-), and Na+SO42-. Careful analyses of the experimental and ab initio results showed, however, that the observed species are of the forms, O-2-M-O-2(-) and O-2-M+O3-. The more interesting M+O-4(2-) and M+O52- species were found to be higher-energy isomers, but they are true minima on the potential energy surfaces, which suggests that it might be possible to synthesize bulk materials containing covalently bound tetra- and pentatomic oxygen building blocks.

  DOI：

  10.1021/ja020097k
• 作为试剂：
  描述：

  反-2-戊烯 在 sodium sulfite 、 甲基磺酰胺 、 AD-mix α 、 对甲苯磺酸 作用下， 以 水 、 叔丁醇 、 正戊烷 为溶剂， 反应 15.0h， 生成 trans-4-Methyl-2,2,5-triaethyl-1,3-dioxolan
  参考文献：
  名称：

  (4S,5S)-2,2,4-Triethyl-5-methyl-1,3-dioxolane: A New Volatile Released by a Triatomine Bug

  摘要：

  Adults of the triatomine bug Triatoma brasiliensis release 2,2,4-triethy1-5-methy1-1,3-dioxolane (1) as a mixture of the (4S,5S)- and (4R,5R)-enantiomers in a ratio of 4:1. Among the volatile acetals identified from insects so far, this is the first example resulting from an intermolecular condensation of a carbonyl moiety and a diol substructure.

  DOI：

  10.1021/ol102165q

文献信息

• Cyclic urea derivatives, pharmaceutical compositions containing these
  申请人：Karl Thomae GmbH

  公开号：US05681841A1

  公开（公告）日：1997-10-28

  The invention relates to cyclic urea derivatives of general formula I ##STR1## wherein R.sub.a, R.sub.b, X and Y are defined as in claim 1, the tautomers, stereoisomers and salts thereof, particularly the physiologically acceptable salts thereof with inorganic or organic acids or bases, which have valuable pharmacological properties, preferably aggregation inhibiting effects, and to drugs containing the compounds and processes for preparing them.

  该发明涉及一般式I的环脲衍生物##STR1##其中R.sub.a、R.sub.b、X和Y的定义如权利要求1中定义的那样，其互变异构体、立体异构体和盐，特别是其与无机或有机酸或碱形成的生理上可接受的盐，具有有价值的药理特性，优选具有聚集抑制作用，并且涉及含有这些化合物的药物和制备它们的方法。
• Cyclic imino derivatives and pharmaceutical compositions containing them
  申请人：Karl Thomae GmbH

  公开号：US05541343A1

  公开（公告）日：1996-07-30

  The invention relates to cyclic imino compounds which have, inter alia, valuable pharmacological properties, especially inhibitory effects on cell aggregation, pharmaceutical compositions which contain these compounds and processes for preparing them.

  这项发明涉及具有有价值的药理特性，特别是对细胞聚集具有抑制作用的环亚胺化合物，包含这些化合物的药物组合物以及制备它们的方法。
• Substituted piperazine derivatives, the preparation thereofand their use as medicaments
  申请人：——

  公开号：US20030166637A1

  公开（公告）日：2003-09-04

  The present invention relates to substituted piperazine derivatives of general formula 1 , (I wherein R a , R b , R c , R f , R g , X, m and n are defined as in claim 1, the isomers and salts thereof, particularly the physiologically acceptable salts thereof, which are valuable inhibitors of the microsomal triglyceride-transfer protein (MTP), medicaments containing these compounds and their use, as well as the preparation thereof.

  本发明涉及一般式1的取代哌嗪衍生物（I），其中Ra、Rb、Rc、Rf、Rg、X、m和n的定义如权利要求书中所述，其异构体和盐，特别是其生理上可接受的盐，这些盐是微粒体甘油三酯转移蛋白（MTP）的有价值的抑制剂，含有这些化合物的药物以及它们的使用，以及其制备。
• A new water-soluble ruthenium(II) carbonyl complex: cis-[Ru(bpy)2(SO3)(CO)]
  作者：Aurideia P. de Sousa、Juliana S. do Nascimento、Alejandro Pedro Ayala、Beatriz Pinheiro Bezerra、Eduardo H.S. Sousa、Luiz G.F. Lopes、Alda K.M. Holanda

  DOI：10.1016/j.poly.2019.04.017

  日期：2019.7

  water solubility calling for improving this drawback. Photolysis of this complex using UV light in aqueous solution leads to high quantum yield of a single CO release. The release of CO was confirmed by myoglobin assay, and a careful monitoring of this photo-reaction was performed using HPLC. Our results showed it might serves as a carbon monoxide releasing moiety, which can be induced photochemically

  摘要一氧化碳对生理学靶标的治疗应用引起了人们的兴趣，这促使我们探索一氧化碳释放分子（CORM's），尤其是那些在特定刺激（即光照射）下分解的分子。在这里，我们制备了一种光活化的，空气稳定的水溶性钌（II）配合物，顺式[[Ru（bpy）2（SO3）（CO）]，在光照射下会释放一氧化碳。确实，许多CORM面临非常有限的水溶性，要求改善这一缺点。在水溶液中使用紫外光对该络合物进行光解可导致单次CO释放的高量子产率。通过肌红蛋白测定证实了CO的释放，并使用HPLC对该光反应进行了仔细的监测。我们的结果表明，它可能充当一氧化碳释放部分，可以通过光化学诱导。
• Herbicidal 2-(oxa or thia
  申请人：Chevron Research Company

  公开号：US04537623A1

  公开（公告）日：1985-08-27

  Herbicidal 2-(oxaheterocycle or thiaheterocycle)-5-amino-3-oxo-4-(substituted-phenyl)-2,3-dihydrofurans and derivatives thereof. The compounds generally exhibit both pre-emergence and post-emergence phytotoxicity and are useful as herbicides and also plant growth regulating agents at low dosages.

  除草剂2-(氧杂杂环或硫杂杂环)-5-氨基-3-氧代-4-(取代苯基)-2,3-二氢呋喃及其衍生物。这些化合物通常表现出前出苗和后出苗的植物毒性，并且在低剂量下可用作除草剂和植物生长调节剂。