Calcium chlorate | 10137-74-3

• 物质功能分类: 无机化工 - 无机盐 - 金属卤化物及卤酸盐
• 分子结构分类: 无机化合物 - 混合金属/非金属化合物 - 碱土金属氧阴离子化合物
• 英文名称: Calcium chlorate
• 英文别名: calcium;dichlorate
• CAS: 10137-74-3
• 化学式: CaCl2O6
• 分子量: 206.98
• InChiKey: YALMXYPQBUJUME-UHFFFAOYSA-L

物化性质

• 熔点：
  340°C
• 密度：
  2.71 g/cm3
• 物理描述：
  Calcium chlorate appears as a white crystalline solid. It forms a very flammable mixture with combustible materials and this mixture may be explosive if the combustible material is finely divided. The mixture can be ignited by friction. Contact with strong sulfuric acid can cause fires or explosions. When mixed with ammonium salts, spontaneous decomposition and ignition may result. Prolonged exposure of the material to fire or heat can result in an explosion. It is used in photography, in pyrotechnics, and as a herbicide.
• 颜色/状态：
  White crystals
• 气味：
  Odorless
• 溶解度：
  197 g/100 g water at 25 °C
• 分解：
  When heated to decomposition it emits toxic fumes of /hydrogen chloride/.

计算性质

• 辛醇/水分配系数(LogP)：
  -7.51
• 重原子数：
  9
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  114
• 氢给体数：
  0
• 氢受体数：
  6

ADMET

毒理性

• 副作用

高铁血红蛋白血症 - 血液中高铁血红蛋白含量增加；该化合物被归类为继发性毒性效应。

Methemoglobinemia - The presence of increased methemoglobin in the blood; the compound is classified as secondary toxic effect

来源:Haz-Map, Information on Hazardous Chemicals and Occupational Diseases

毒理性

• 解毒与急救

紧急和对症治疗：保持呼吸道通畅，必要时辅助呼吸。如果出现昏迷、溶血、高钾血症、肾脏或肝脏衰竭，则进行治疗。大量溶血可能需要输血。为了防止由于游离血红蛋白在肾小管中沉积导致的肾衰竭，给予静脉输液和碳酸氢钠。/氯酸盐/

Emergency and supportive treatment: Maintain on open airway and assist ventilation if necessary. Treat coma, hemolysis, hyperkalemia, and renal or hepatic failure if they occur. Massive hemolysis may require blood transfusions. To prevent renal failure resulting from deposition of free hemoglobin in the kidney tubules, administer intravenous fluids and sodium bicarbonate. /Chlorates/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

特定的药物和解毒剂：用亚甲基蓝治疗高铁血红蛋白血症，... 亚甲基蓝在轻度病例的早期使用时效果最好，但在已经发生溶血的严重病例中效果不佳。静脉注射硫代硫酸钠可能使氯酸根离子失活，并在个案报告中取得成功。然而，这种治疗方法尚未经过临床测试。作为灌洗液使用可能会产生一些硫化氢，因此是禁忌的。/氯酸盐/

Specific drugs and antidotes: Treat methemoglobinemia with methylene blue, ... . Methylene blue is reportedly most effective when used early in mild cases but has poor effectiveness in severe cases in which hemolysis has already occurred. Intravenous sodium thiosulfate may inactivate the chlorate ion and has been reported to be successful in anecdotal reports. However, this treatment has not been clinically tested. Administration as a lavage fluid may potentially produce some hydrogen sulfide, and so it is contraindicated. /Chlorates/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

紧急和支持性措施：保持呼吸道通畅，必要时辅助呼吸。用静脉晶体液治疗胃肠炎引起的液体丢失。连接心电监护仪，并在摄入后至少密切观察患者6-8小时。/钡餐/

Emergency and supportive measures: Maintain on open airway and assist ventilation if necessary. treat fluid losses from gastroenteritis with intravenous crystalloids. Attach a cardiac monitor and observe the patient closely for at least 6-8 hours after ingestion. /Barium/

来源:Hazardous Substances Data Bank (HSDB)

毒理性

• 解毒与急救

Decontamination: 活性炭可能不会吸附钡，除非有其他共食物质，否则不推荐使用。对于大量近期摄入的情况，应进行洗胃。口服硫酸镁或硫酸钠......以沉淀摄入的钡，形成不溶的硫酸盐。/钡/

Decontamination: Activated charcoal probably does not adsorb barium and is not recommended unless there are co-ingestants. Perform gastric lavage for a large recent ingestion. Magnesium sulfate or sodium sulfate ... should be administered orally to precipitate ingested barium as the insoluble sulfate salt. /Barium/

来源:Hazardous Substances Data Bank (HSDB)

安全信息

• 危险等级：
  5.1
• 危险品运输编号：
  1452
• 包装等级：
  II
• 危险类别：
  5.1

制备方法与用途

水中溶解度(g/100ml)：每100毫升水中的溶解克数为209g（20℃）

类别 氧化剂

毒性分级 中毒

急性毒性

• 口服：大鼠 LD50: 4500 毫克/公斤
• 腹注：大鼠 LD50: 625 毫克/公斤

爆炸物危险特性 遇有机物、金属粉末可爆

可燃性危险特性

• 遇热放氧
• 遇有机物、金属粉末可燃
• 热分解排出有毒氯化物烟雾

储运特性 应存放在通风低温干燥的库房内，并与燃料、有机物、还原剂及金属末分开存放

灭火剂 使用水进行灭火