2-(4-Oxothieno[2,3-d]pyrimidin-3-yl)acetamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻吩并嘧啶酮衍生物
• 英文名称: 2-(4-Oxothieno[2,3-d]pyrimidin-3-yl)acetamide
• 化学式: C₈H₇N₃O₂S
• mdl: MFCD08000180
• 分子量: 209.23
• InChiKey: KTXYVSBKZWAGRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.2
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.125
• 拓扑面积：
  104
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• Antiviral Drugs for Treatment or Prevention of Dengue Infection
  申请人：Byrd Chelsea M.

  公开号：US20100189685A1

  公开（公告）日：2010-07-29

  Compounds, methods and pharmaceutical compositions for treating viral infections, by administering certain compounds in therapeutically effective amounts are disclosed. Methods for preparing the compounds and methods of using the compounds and pharmaceutical compositions thereof are also disclosed. In particular, the treatment and prophylaxis of viral infections such as caused by flavivirus is disclosed, i.e., including but not limited to, Dengue virus, West Nile virus, yellow fever virus, Japanese encephalitis virus, and tick-borne encephalitis virus.