双三甲基硅基磷酸氢酯 | 55518-04-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 中文名称: 双三甲基硅基磷酸氢酯
• 英文名称: bis(trimethylsiloxy)phosphoric acid
• 英文别名: phosphate de bis (trimethylsilyle)；bis(trimethylsilyl)phosphate；bis-trimethylsilylhydrogenphosphate；Bis(trimethylsilyl) hydrogen phosphate
• CAS: 55518-04-2
• 化学式: C₆H₁₉O₄PSi₂
• 分子量: 242.359
• InChiKey: HVGFMUJLKBGRSF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.79
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  三异丁基铝 、 双三甲基硅基磷酸氢酯 以 正己烷 为溶剂， 反应 48.0h， 以65%的产率得到[(AliBu2{μ2-O2P(OSiMe3)2})2]
  参考文献：
  名称：

  Construction of Larger Molecular Aluminophosphate Cages from the Cyclic Four-Ring Building Unit

  摘要：

  New molecular aluminophosphates of different nuclearity are synthesized by a stepwise process and structurally characterized. The alkane elimination reaction of bis(trimethylsiloxy)phosphoric acid, OP-(OH)(OSiMe3)(2), with trialkylalanes, AlR3 (R = Me, Et, Bu-i), provides the cyclic dimeric aluminophosphates, [(AlR2{mu(2)-O2P(OSiMe3)(2)})(2)) (R = Me (1), Et (2), Bu-i (3)). Unsymmetrically substituted cyclic aluminophosphonate [(AlMe2{mu(2)-O2P(OSiMe3)((c)Hex)})(2)] (cis/trans-4) is prepared by dealkylsilylation reaction of (c)HexP(O)(OSiMe3)(2) with AlMe3. Molecules 1-4 containing the [Al-2(mu(2)-O2P)(2)] inorganic core are structural and spectroscopic models for the single four-ring (S4R) secondary building units (SBU) of zeolite frameworks. Compound 1 serves as a starting point in construction of larger molecular units by reactions with OP(OH)(OSiMe3)(2) as a cage-extending reagent and with diketones, such as Hhfacac (1,1,1,5,5,5-hexafluoropentan-2,4-dione) and Hacac (pentan-2,4-dione), as capping reagents. Reaction of 1 with 4 equiv of Hhfacac leads to new cyclic aluminophosphate [(Al(hfacac)(2){mu(2)-O2P(OSiMe3)(2)})(2)] (5), existing in two isomeric (D-2 and C-2h) forms. Reaction of 1 with 2 equiv of OP(OH)(OSiMe3)(2) and 1 equiv of Hhfacac provides a molecular aluminophosphate [AlMe{Al(hfacac)}(2){mu(3)-O3P(OSiMe3)}(2){mu(2)-O2P(OSiMe3)(2)}(2){OP-(OSiMe3)(3)}] (6), while by adding first the Hhfacac and using 3 equiv of OP(OH)(OSiMe3)(2) we isolate [Al{Al(hfacac)}(2){mu(3)-O3P(OSiMe3)}(2){mu(2)-O2P(OSiMe3)(2)}(2)H{OP(O)(OSiMe3)(2)}(2)] (7). These molecules contain units in their cores that imitate 4=1 SBU of zeolite frameworks. Reaction with the order of component mixing 1, Hhfacac, OP(OH)(OSiMe3)(2) at a 1:2:2 molar ratio lead to formation of a larger cluster [(Al(AlMe){Al(hfacac)}{mu(3)-O3P(OSiMe3)}(2){mu(2)-O2P(OSiMe3)(2)}(3))(2)] (8) containing both S4R and 4=1 structural units. Similarly, Hacac (pentan-2,4-dione) provides an isostructural [Al(AlMe){Al(acac)}{mu(3)-O3P(OSiMe3)}(2){mu(2)-O2P(OSiMe3)(2)}(3))(2)] (9). Both molecules display Al centers in three different coordination environments.

  DOI：

  10.1021/ic500083a
• 作为产物：
  描述：

  三甲基氯硅烷 在 磷酸 、 三乙胺 作用下， 以 1,4-二氧六环 为溶剂， 以95%的产率得到双三甲基硅基磷酸氢酯
  参考文献：
  名称：

  通过甲硅烷基化中间体对羟基进行磷酸化

  摘要：

  从甲硅烷基化醇开始的新颖途径已经制备了生物学上感兴趣的烯丙基磷酸酯。

  DOI：

  10.1002/recl.19881070909

文献信息

• Nonaqueous synthesis of molecular zinc amide phosphate
  作者：Jan Chyba、Zdenek Moravec、Marek Necas、Sanjay Mathur、Jiri Pinkas

  DOI：10.1016/j.jorganchem.2013.09.040

  日期：2014.1

  Three new molecular zinc compounds were prepared by nonaqueous reactions of Zn[N(SiMe3)(2)](2) and ZnEt2 with trimethylsilylesters of phosphoric acid, OP(OSiMe3)(3) and OP(OSiMe3)(2)(OH). Single-crystal Xray diffraction analyses of crystalline products revealed molecular structures of two mononuclear complexes [ZnX2OP(OSiMe3)(3)] (X = N(SiMe3)(2) (1), hfacac = hexafluoroacetylacetonate, (2)) and one dinuclear zinc phosphate [(Zn(py)N(SiMe3)(2)}mu(2)-O2P(OSiMe3)(2)})(2)] (3). Compound 1 is only the second structurally characterized adduct of zinc bisamide with an oxygen donor and a three-coordinate Zn atom. The cyclic inorganic core Zn(mu(2)-O2PO2)}(2) in 3 is a model for the most common single four-ring (S4R) building unit of open-framework zinc phosphates. The molecule of 3 possesses reactive amide and tri-methylsiloxy groups that can be employed in further studies on the formation of extended structures by condensation reactions. Spectroscopic properties and thermal behavior of the molecular products were examined. Compounds 1 and 3 were converted to alpha-Zn2P2O7 by calcination. (C) 2013 Elsevier B. V. All rights reserved.
• Lazukina, L. A.; Kukhar, V. P., Journal of general chemistry of the USSR, 1990, vol. 60, # 3.2, p. 608
  作者：Lazukina, L. A.、Kukhar, V. P.

  DOI：——

  日期：——
• MONTERO, JEAN-LOUIS;TOIRON, CATHERINE;CLAVEL, JEAN-LOUIS;IMBACH, JEAN-LOU+, REC. TRAV. CHIM. PAYS-BAS, 107,(1988) N 9, C. 570-572
  作者：MONTERO, JEAN-LOUIS、TOIRON, CATHERINE、CLAVEL, JEAN-LOUIS、IMBACH, JEAN-LOU+

  DOI：——

  日期：——