3-[10-(2,4-dichloro-phenyl)-7,7-dimethyl-9-oxo-5,6,7,8,9,10-hexahydro-3,5,11-triaza-dibenzo[a,d]cyclohepten-11-yl]-3-oxo-propionitrile | 1047618-86-9

分子结构分类

有机化合物 - 有机杂环化合物 - 吡啶二氮卓类

中文名称

——

中文别名

——

英文名称

3-[10-(2,4-dichloro-phenyl)-7,7-dimethyl-9-oxo-5,6,7,8,9,10-hexahydro-3,5,11-triaza-dibenzo[a,d]cyclohepten-11-yl]-3-oxo-propionitrile

英文别名

3-[6-(2,4-Dichlorophenyl)-9,9-dimethyl-7-oxo-6,8,10,11-tetrahydropyrido[3,4-b][1,4]benzodiazepin-5-yl]-3-oxo-propanenitrile；3-[6-(2,4-dichlorophenyl)-9,9-dimethyl-7-oxo-6,8,10,11-tetrahydropyrido[3,4-b][1,4]benzodiazepin-5-yl]-3-oxopropanenitrile

3-[10-(2,4-dichloro-phenyl)-7,7-dimethyl-9-oxo-5,6,7,8,9,10-hexahydro-3,5,11-triaza-dibenzo[a,d]cyclohepten-11-yl]-3-oxo-propionitrile化学式

CAS

1047618-86-9

化学式

C₂₃H₂₀Cl₂N₄O₂

mdl

——

分子量

455.343

InChiKey

UHAOFAYPWZHAPR-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

3.7
重原子数：

31
可旋转键数：

2
环数：

4.0
sp3杂化的碳原子比例：

0.3
拓扑面积：

86.1
氢给体数：

1
氢受体数：

5

反应信息

作为产物：

描述：

3-[(4-Aminopyridin-3-yl)amino]-5,5-dimethylcyclohex-2-en-1-one 在溶剂黄146 、三乙胺作用下，以乙醇、二氯甲烷为溶剂，反应 67.5h，生成 3-[10-(2,4-dichloro-phenyl)-7,7-dimethyl-9-oxo-5,6,7,8,9,10-hexahydro-3,5,11-triaza-dibenzo[a,d]cyclohepten-11-yl]-3-oxo-propionitrile

参考文献：

名称：

WO2008/99021

摘要：

公开号：

点击查看最新优质反应信息

文献信息

WO2008/99021

申请人：——

公开号：——

公开（公告）日：——

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