4-Tolyl-4'-hydroxybenzoat | 65664-73-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: 4-Tolyl-4'-hydroxybenzoat
• 英文别名: 4-Hydroxy-benzoic acid p-tolyl ester；(4-methylphenyl) 4-hydroxybenzoate
• CAS: 65664-73-5
• 化学式: C₁₄H₁₂O₃
• 分子量: 228.247
• InChiKey: ZNKVAMPOPOVQQU-UHFFFAOYSA-N

物化性质

• 沸点：
  387.3±25.0 °C(Predicted)
• 密度：
  1.216±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-Tolyl-4'-hydroxybenzoat 、 (4'-methylcyclohex-3'-ene-1-'-yl)carbonyl chloride 在 吡啶 作用下， 以 乙醚 为溶剂， 反应 6.0h， 以42%的产率得到(4-methylphenyl) 4-(4-methylcyclohex-3-ene-1-carbonyl)oxybenzoate
  参考文献：
  名称：

  Bezborodov, V. S.; Lapanik, V. I.; Grinkevich, O. A., Journal of Organic Chemistry USSR (English Translation), 1987, vol. 23, p. 135 - 137

  摘要：

  DOI：

文献信息

• Liquid crystal medium and liquid display
  申请人：Wittek Michael

  公开号：US10450509B2

  公开（公告）日：2019-10-22

  Mesogenic media comprising one or more compounds of formulae I or II preferably mesogenic media showing a blue phase, preferably stabilized by a polymer, and their use in electro-optical light modulation elements and their respective use in displays, as well as such devices.

  含有一个或多个I或II式化合物的介向介质，优选显示蓝相的介向介质，优选由聚合物稳定，并且它们在电光调制元件中的使用以及它们在显示器中的相应使用，以及这些装置。
• NUCLEOTIDE AND OLIGONUCLEOTIDE PRODRUGS
  申请人：Iyer Radhakrishnan P.

  公开号：US20120264709A1

  公开（公告）日：2012-10-18

  The present invention discloses compounds of formula (I): which exhibit antiviral properties. The present invention further relates to pharmaceutical compositions comprising the aforementioned compounds for administration to a subject in need of anti-HBV treatment. The invention also relates to methods of treating a HBV infection in a subject by administering a pharmaceutical composition comprising the compounds of the present invention.

  本发明揭示了式（I）的化合物：具有抗病毒特性。本发明还涉及包含上述化合物的制药组合物，用于治疗需要抗HBV治疗的受试者。本发明还涉及通过给予包含本发明化合物的制药组合物来治疗受试者的HBV感染的方法。
• Novel wholly aromatic copolyester, process for production thereof, and film melt-shaped therefrom
  申请人：TEIJIN LIMITED

  公开号：EP0045499A2

  公开（公告）日：1982-02-10

  A wholly aromatic copolyester composed mainly of isophthalic acid units and hydroquinone units, the total proportion of said isophthalic acid units and hydroquinone units being at least about 80 mole% based on the entire units, said wholly aromatic copolyester having a terminal carboxyl group concentration, measured by the method described in the specification, of not more than about 90 eq/106 g and a reduced viscosity, determined at 35°C in a mixed solvent of phenol and tetrachloroethane in a weight ratio of 4:6 in a concentration of 1.2 gfdl of at least about 0.6 and being substantially linear and melt-shapable and substantially free from a halogen atom bonded to the molecular chain, and a film prepared therefrom by melt shaping. The wholly aromatic copolyester can be prepared by a process which comprises polycondensing under heat in the presence of a polycondensation catalyst (a) a reaction mixture consisting of a major proportion of a diaryl ester of isophthalic acid and hydroquinone and a minor proportion of at least one other component selected from diaryl esters of aromatic dicarboxylic acids other than isophthalic acid, aromatic dihydroxy compounds other than hydroquinone and aryl hydroxyenboates or (b) a reaction mixture consisting of a major proportion of isophthalic acid, hydroquinone and a diaryl carbonate and a minor proportion of at least one other component selected from aromatic dicarboxylic acids other than isophthalic acid, aromatic dihydroxy compounds other than hydroquinone, hydroxybenzoic acid and aryl hydroxybenzoates, and after the reduced viscosity of the polymer formed in the reaction system has reached about 0.2, performing the polycondensation at a temperature lower than the crystalline melting point of the polymer while maintaining the reaction system in a molten condition; or which comprises polymerizing the wholly aromatic copolyester having a reduced viscosity of at least 0.6 prepared by the above process or a wholly aromatic copolyester having a reduced viscosity of less than about 0.6 in the solid phase in a manner known per se under reduced pressure or while passing an inert gas into the reaction system. The film can be used as films for metal vapor depocition, films for printed circuits and electrical insulating films by using their excellent heat resistance.

  一种主要由间苯二甲酸单元和对苯二酚单元组成的全芳香族共聚聚酯，所述间苯二甲酸单元和对苯二酚单元的总比例以整个单元为基准至少约为 80 摩尔％，所述全芳香族共聚聚酯的末端羧基浓度（用说明书所述方法测定）不超过约 90 eq/106 g，在 35°C 时，在重量比为 4:6 的苯酚和四氯乙烷混合溶剂中测定的降低粘度为 1.2 gfdl至少约为0.6，基本上呈线性，可熔融成型，基本上不含与分子链键合的卤原子，以及由其通过熔融成型制备的薄膜。 全芳香族共聚聚酯可通过以下工艺制备： 在缩聚催化剂存在下，在加热条件下进行缩聚 (a) 反应混合物，其主要成分为间苯二甲酸二芳基酯和对苯二酚，次要成分为至少一种选自间苯二甲酸以外的芳香族二羧酸二芳基酯的其他成分、或 (b) 反应混合物，其主要成分为间苯二甲酸、对苯二酚和碳酸二芳基酯，次要成分为至少一种选自间苯二甲酸以外的芳香族二羧酸、对苯二酚以外的芳香族二羟基化合物、羟基苯甲酸和羟基苯甲酸芳基酯的其他成分。2，在低于聚合物结晶熔点的温度下进行缩聚，同时将反应体系保持在熔融状态；或者包括在减压或向反应体系通入惰性气体的情况下，以本身已知的方式在固相中聚合通过上述工艺制备的粘度降低至少为 0.6 的全芳香族共聚聚酯或粘度降低小于约 0.6 的全芳香族共聚聚酯。 这种薄膜具有优异的耐热性，可用作金属蒸镀薄膜、印刷电路薄膜和电绝缘薄膜。
• Process for producing a film-like and fibrous article of a wholly aromatic polyester
  申请人：TEIJIN LIMITED

  公开号：EP0070539A1

  公开（公告）日：1983-01-26

  A wholly aromatic polyester composition comprising (a) 100 parts by weight of a wholly aromatic polyester containing as a main component at least one compound selected from the group consisting of aromatic dicarboxylic acids, aromatic dihydroxy compounds and aromatic hydroxycarboxylic acids, and (b) from 5 to 300 parts by weight of a low-molecular-weight compound being substantially non-reactive with the wholly aromatic polyester and having a boiling point of at least about 200°C under atmospheric pressure and a molecular weight of not more than 1.000. The wholly aromatic polyester composition is produced advantageously by polycondensing in the molten state the polyester-forming starting mixture in the presence of the low-molecular-weight compound. A film-like or fibrous article of a wholly aromatic polyester may be produced by extracting the low-molecular-weight compound from a film-like or fibrous article of the wholly aromatic polyester composition.

  全芳香族聚酯组合物，包括 (a) 100 份（按重量计）全芳香族聚酯，其主要成分含有至少一种选自芳香族二 羧酸、芳香族二羟基化合物和芳香族羟基羧酸的化合物，以及 (b) 5 至 300 重量份的低分子量化合物，该化合物与全芳香族聚酯基本不发生 反应，在常压下沸点至少约为 200℃，分子量不超过 1.000。 全芳香族聚酯组合物的有利生产方法是在低分子量化合物存在下，在熔融状态下对聚酯形成起始混合物进行缩聚。 全芳香族聚酯的薄膜状或纤维状制品可通过从全芳香族聚酯组合物的薄膜状或纤维状制品中提取低分子量化合物而制成。
• Fluoran compounds and recording sheets containing them
  申请人：KANZAKI PAPER MANUFACTURING CO., LTD

  公开号：EP0155593A2

  公开（公告）日：1985-09-25

  Fluoran compounds of the structural formula: wherein R1 is propyl or butyl, R2 is an alkyl of from one to four carbon atoms, R3 is methyl or ethyl, and R4 is hydrogen or methyl are particularly suitable for use in providing high quality pressure, heat or electrothermal sensitive recording sheets containing a color former in operative association with an electron-accepting substance.

  结构式如下的氟化合物 其中 R1 是丙基或丁基，R2 是一至四个碳原子的烷基，R3 是甲基或乙基，R4 是氢或甲基，这些氟化合物特别适用于提供高质量的压力、热量或电热敏感记录片，该记录片含有与电子接受物质有效结合的显色剂。