Methyl (1S,17R)-17-(2-methoxyethyl)-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate | 308123-60-6

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 依波格型生物碱
• 英文名称: Methyl (1S,17R)-17-(2-methoxyethyl)-3,13-diazapentacyclo[13.3.1.02,10.04,9.013,18]nonadeca-2(10),4,6,8-tetraene-1-carboxylate
• CAS: 308123-60-6
• 化学式: C₂₂H₂₈N₂O₃
• 分子量: 368.5
• InChiKey: DTJQBBHYRQYDEG-YHIIEBRDSA-N

物化性质

• 沸点：
  510.1±50.0 °C(Predicted)
• 密度：
  1.25±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  27
• 可旋转键数：
  5
• 环数：
  6.0
• sp3杂化的碳原子比例：
  0.59
• 拓扑面积：
  54.6
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• SYSTEMS AND METHODS FOR GEL-BASED NEUROMODULATION
  申请人：Tulavi Therapeutics, Inc.

  公开号：EP3764990A1

  公开（公告）日：2021-01-20
• [EN] SYSTEMS AND METHODS FOR GEL-BASED NEUROMODULATION<br/>[FR] SYSTÈMES ET PROCÉDÉS DE NEUROMODULATION À BASE DE GEL
  申请人：TULAVI THERAPEUTICS INC

  公开号：WO2019178564A1

  公开（公告）日：2019-09-19

  Methods, devices and systems are described for gel-based modulation of neural tissue, including prevention of nerve regeneration and neuroma formation. The gel can be delivered to selected target locations within or proximate nerves, including interfascicularly and intrafascicularly. Gel delivery associated with an operative procedure for the treatment of pain and other indications is also disclosed.