trans-4-(N-acetylamino)azobenzene | 30808-70-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: trans-4-(N-acetylamino)azobenzene
• 英文别名: 4-(N-acetylamino)azobenzene；4-phenylazoacetanilide；4-phenylazo-N-acetylaniline
• CAS: 30808-70-9
• 化学式: C₁₄H₁₃N₃O
• 分子量: 239.277
• InChiKey: WSHHPNYAXLDUTG-WUKNDPDISA-N

物化性质

• 熔点：
  144-146 °C
• 沸点：
  462.2±28.0 °C(Predicted)
• 密度：
  1.13±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.06
• 重原子数：
  18.0
• 可旋转键数：
  3.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.07
• 拓扑面积：
  53.82
• 氢给体数：
  1.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  trans-4-(N-acetylamino)azobenzene 在 C₉₆H₁₄₄N₃₆Pd₆⁽¹²⁺⁾*2C₁₄H₁₄BF₅N₂ 作用下， 以 水 为溶剂， 生成 4-acetamidoazobenzene
  参考文献：
  名称：

  限制下可见光敏化使偶氮苯失衡

  摘要：

  偶氮苯从稳定的光致异构化乙亚稳态异构体Z状态是这些分子众多应用的基础。然而，该反应通常需要紫外光，这限制了适用性。在这项研究中，我们引入了限制下敏化（DESC）的不平衡，这是一种诱导乙-到-Z通过使用所需颜色的光（包括红色）进行异构化。DESC 依赖于大环主体和光敏剂的组合，它们共同作用以选择性地结合和敏化乙-偶氮苯用于异构化。这Z异构体对宿主缺乏强亲和力，会被宿主排出，然后宿主可以转化额外的电子-偶氮苯对Z状态。通过这种方式，主体-光敏剂复合物将光子能量以非平衡光稳态的形式转化为化学能，包括那些无法通过直接光激发获得的状态。

  DOI：

  10.1126/science.adh9059
• 作为产物：
  描述：

  4-acetamidoazobenzene 生成 trans-4-(N-acetylamino)azobenzene
  参考文献：
  名称：

  Kerzhner, B. K.; Vrubel', T. L.; Kofanov, V. I., Journal of general chemistry of the USSR, 1987, p. 1049 - 1052

  摘要：

  DOI：

文献信息

• Method Of Preparing Fused Ring Indeno Compounds
  申请人：Transitions Optical, Inc.

  公开号：US20150141662A1

  公开（公告）日：2015-05-21

  The present invention relates to methods of preparing fused ring indeno compounds that involves reacting together a dienophile and a lactone compound, in the presence of a catalyst, and a carboxylic acid anhydride. With some embodiments, the fused ring indeno compound is represented by the following Formula (I-A), the dienophile is represented by the following Formula (II-A), and the lactone compound is represented by the following Formula (III-A):

  本发明涉及一种制备融合环吲哚化合物的方法，涉及将双亲受体和内酯化合物在催化剂和羧酸酐的存在下反应在一起。在某些实施例中，融合环吲哚化合物由以下式(I-A)表示，双亲受体由以下式(II-A)表示，内酯化合物由以下式(III-A)表示：
• Photochromic Indeno-Fused Ring Pyran Compounds
  申请人：Transitions Optical, Inc.

  公开号：US20150141661A1

  公开（公告）日：2015-05-21

  The present invention relates to photochromic indeno-fused ring pyran compounds represented by the following Formula (I-A): The present invention also relates to photochromic dichroic compounds, such as represented by Formula (I-A), in which (i) Z 2 is a group N—R 13 in which R 13 is a group L, and (ii) optionally at least one R 1 independently for each n is selected from a group L, in which the group L independently in each case is a lengthening group that provides the photochromic compound with dichroic properties, in accordance with some embodiments. The present invention also relates to photochromic articles, such as photochromic ophthalmic articles, that include one or more photochromic compounds according to the present invention, such as represented by Formula (I-A).

  本发明涉及由以下式（I-A）表示的光致变色吲哚融合环吡喃化合物。本发明还涉及光致二向色化合物，例如由式（I-A）表示，其中（i）Z2是一个N—R13基团，其中R13是一个L基团，以及（ii）对于每个n，可选地至少选择一个R1，每种情况下独立选择自L基团，其中每种情况下L基团是一个提供光致化合物二向色性能的延伸基团，符合某些实施例。本发明还涉及光致物品，例如光致眼科物品，包括根据本发明的一个或多个光致化合物，例如由式（I-A）表示。
• ABCA-1 elevating compounds
  申请人：——

  公开号：US20030220356A1

  公开（公告）日：2003-11-27

  The present invention provides compounds that elevate cellular expression of the ABCA-1 gene, promoting cholesterol efflux from cells and increasing HDL levels in the plasma of a mammal, in particular humans. The compounds are useful for treating coronary artery disease.

  本发明提供了一种能够提高ABCA-1基因细胞表达的化合物，促进胆固醇从细胞中流出并增加哺乳动物（尤其是人类）血浆中的高密度脂蛋白水平。这些化合物可用于治疗冠心病。
• Photoresponsive peptoid oligomers bearing azobenzene side chains
  作者：Neel H. Shah、Kent Kirshenbaum

  DOI：10.1039/b804802a

  日期：——

  N -Substituted glycine peptoid oligomers were synthesized to incorporate a photoresponsive azobenzene side chain. The ability of this side chain to undergo reversible photoisomerization was established, and the cis- to trans-azobenzene thermal isomerization of this side chain was investigated. Circular dichroism studies indicated that trans- to cis-azobenzene isomerization does not significantly alter the backbone conformation in a series of peptoids thought to have well-defined structures.

  我们合成了含有光致伸缩性偶氮苯侧链的 N - 取代甘氨酸肽类低聚物。研究人员确定了这种侧链进行可逆光异构化的能力，并对这种侧链的顺式到反式偶氮苯热异构化进行了研究。环二色性研究表明，反式偶氮苯到顺式偶氮苯的异构化并不会显著改变一系列被认为具有明确结构的拟肽类化合物的骨架构象。
• Fused Ring Indeno Compounds For Preparation Of Photochromic Compounds
  申请人：Transitions Optical, Inc.

  公开号：US20150141663A1

  公开（公告）日：2015-05-21

  The present invention relates to intermediate compounds represented by the following Formula (I-A), The intermediate compounds of the present invention, such as represented by Formula (I-A), can be used to prepare photochromic compounds, such as photochromic fused ring indenopyran compounds, including but not limited to photochromic fused ring indeno-naphtho-pyran compounds.

  本发明涉及以下式(I-A)所表示的中间化合物。本发明的中间化合物，如式(I-A)所示，可用于制备光致变色化合物，例如光致变色融合环吲哚吡喃化合物，包括但不限于光致变色融合环吲哚萘吡喃化合物。

表征谱图