Dibutyl-octadecylphosphoramidat | 65289-16-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: Dibutyl-octadecylphosphoramidat
• 英文别名: N-dibutoxyphosphoryloctadecan-1-amine
• CAS: 65289-16-9
• 化学式: C₂₆H₅₆NO₃P
• 分子量: 461.709
• InChiKey: BPWFGYBGLLYEGE-UHFFFAOYSA-N

物化性质

• 沸点：
  514.1±33.0 °C(Predicted)
• 密度：
  0.917±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  10.6
• 重原子数：
  31
• 可旋转键数：
  26
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  十八胺 、 氯磷酸二正丁基酯 在 三乙胺 作用下， 生成 Dibutyl-octadecylphosphoramidat
  参考文献：
  名称：

  Bebikh,G.F. et al., Journal of general chemistry of the USSR, 1977, vol. 47, p. 2005 - 2008

  摘要：

  DOI：

文献信息

• ELECTRONIC DETECTION OF A TARGET BASED ON ENZYMATIC CLEAVAGE OF A REPORTER MOIETY
  申请人：AMMR Joint Venture

  公开号：EP3990630A1

  公开（公告）日：2022-05-04
• [EN] ELECTRONIC DETECTION OF A TARGET BASED ON ENZYMATIC CLEAVAGE OF A REPORTER MOIETY<br/>[FR] DÉTECTION ÉLECTRONIQUE D'UNE CIBLE SUR LA BASE D'UN CLIVAGE ENZYMATIQUE D'UNE FRACTION RAPPORTEUR
  申请人：AMMR JOINT VENTURE

  公开号：WO2020264204A1

  公开（公告）日：2020-12-30

  Apparatuses, systems, and methods are disclosed for target detection based on collateral cleavage of a reporter (730) by an enzyme (720). A biologically gated transistor (106) may include a channel (710) and a reporter moiety (730) immobilized to the channel (710). The state of the reporter moiety (730) affects output signals from the biologically gated transistor (106) when excitation conditions are applied to the biologically gated transistor (106) and a sample fluid (110) is applied in contact with the channel (710). A sample fluid (110) may include an enzyme (720) configured to activate in response to a target nucleic acid (722) to cleave the reporter moiety (730). Excitation circuitry (1502) applies the excitation conditions, and measurement circuitry (1504) measures output signals from the biologically gated transistor (106). An analysis module (116) determines a parameter relating to presence of the target nucleic acid (722), based on the one or more measurements.