申请人:Mahant Vijay K.
公开号:US20090081717A1
公开(公告)日:2009-03-26
Improved assay systems comprise a substrate that is modified to include a solubilizing group and/or an at least binary solvent system to provide significantly enhanced signal strength and signal-to-noise ratio. In especially preferred aspects, the assay system is a chromogenic, electrochemical, and/or luminogenic assay system in which an indoxyl-type substrate has a solubilizing group covalently attached to the substrate and/or in which a polar and non-protic solvent is used as a co-solvent.