salicyl gallate | 1030868-24-6

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: salicyl gallate
• 英文别名: 2-(3,4,5-Trihydroxybenzoyl)oxybenzoic acid
• CAS: 1030868-24-6
• 化学式: C₁₄H₁₀O₇
• 分子量: 290.229
• InChiKey: IVTVKPUQAUWMPY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  21
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  124
• 氢给体数：
  4
• 氢受体数：
  7

文献信息

• ANTI-OBESITY AGENT COMPRISING COMPOUND CONTAINING BENZOTROPOLONE RING
  申请人：Fukui Yuko

  公开号：US20120065410A1

  公开（公告）日：2012-03-15

  The object of the present invention is to provide an anti-obesity agent which contains a tea-derived component and which is safe and does not compromise the flavor of foods and beverages. According to the present invention, a safe and palatable anti-obesity agent can be provided by incorporating a benzotropolone ring-containing compound which has tea-derived, high inhibitory activities against lipase and alfa-glucosidase. The anti-obesity agent of the present invention does not compromise the flavor of foods and beverage, has palatability, and can be used in various use applications including foods and beverages intended for health enhancement such as reduction in triglycerides.

  本发明的目的是提供一种抗肥胖剂，其中包含一种来源于茶叶的成分，既安全又不会影响食品和饮料的味道。根据本发明，通过将含苯并环戊酮环的化合物纳入其中，可以提供一种安全而美味的抗肥胖剂，该化合物具有来源于茶叶的高抑制脂肪酶和α-葡萄糖苷酶的活性。本发明的抗肥胖剂不会影响食品和饮料的味道，具有口感，可以用于各种用途，包括旨在提高健康的食品和饮料，如降低三酰甘油。
• Novel compound having inhibitory effect on lipase
  申请人：Nakai Masaaki

  公开号：US20110118344A1

  公开（公告）日：2011-05-19

  This invention provides, a novel polyphenol compound having lipase inhibitory activity derived from tealeaves, a process for the preparation of the compound, and foods and/or beverages and pharmaceutical drugs containing the compound. Particularly, this invention provides a novel dimer compound of formula: obtained by oxidative polymerization of epigallocatechin-3-O-gallate, a main catechin component of oolong tea, with a tealeaf enzyme (polyphenol oxidase), as well as foods and/or beverages and pharmaceutical compositions containing said novel compound which suppress absorption of dietary lipids and suppresses increase of blood triglyceride.

  本发明提供了一种从茶叶中提取的具有抑制脂肪酶活性的新型多酚化合物，一种制备该化合物的方法，以及包含该化合物的食品和/或饮料和药物。特别地，本发明提供了一种新型二聚体化合物，其化学式为：通过茶叶酶（多酚氧化酶）氧化聚合茶多酚中的主要儿茶素成分表沙龙茶素-3-O-没食子酸酯得到，以及包含该新型化合物的食品和/或饮料和药物组合物，其抑制膳食脂肪的吸收并抑制血液甘油三酯的增加。
• EPIGALLOCATECHIN DIMERS OR TRIMERS HAVING LIPASE INHIBITORY ACTIVITY AND/OR ANTIOXIDATIVE ACTIVITY
  申请人：Suntory Holdings Limited

  公开号：EP1754702B1

  公开（公告）日：2012-03-07
• EPIGALLOCATECHIN DIMERS OR TRIMERS HAVING LIPASE INHIBITORY ACTIVITY AND/OR ANTIOXIDANT ACTIVITY
  申请人：NAKAI Masaaki

  公开号：US20110124887A1

  公开（公告）日：2011-05-26

  An object of the present invention is to provide a lipase activity inhibitor that shows high inhibitory activity against pancreatic lipase to suppress the absorption of meal-derived fat and/or which contributes to suppressing and preventing obesity, as well as a food or beverage that has such lipase activity inhibitor incorporated therein. Another object of the invention is to provide a lipase inhibitor of tea origin that suits most consumers' taste and which will not impair the flavor of the food or beverage when incorporated therein. Still another object of the invention is to provide a process for producing said lipase inhibitors. Further object of the invention is to provide antioxidants. To attain these objects, epigallocatechin dimers (oolong homobisflavans) or trimers are incorporated in foods or beverages. As a result, the absorption of meal-derived fat can be suppressed and, in addition, antioxidation effect is obtained. The compounds of the invention can be produced by reacting epigallocatechin gallate with formaldehyde in the presence of an acid.
• US7939559B2
  申请人：——

  公开号：US7939559B2

  公开（公告）日：2011-05-10