5-(3-chloro-phenylazo)-2-hydroxy-benzoic acid ethyl ester | 21461-01-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 5-(3-chloro-phenylazo)-2-hydroxy-benzoic acid ethyl ester
• 英文别名: 5-(3-Chlor-phenylazo)-2-hydroxy-benzoesaeure-aethylester；3'-Chlor-4-oxy-azobenzol-carbonsaeure-(3)-aethylester；(3-Chlor-benzol)-(1 azo 5)-salicylsaeure-aethylester
• CAS: 21461-01-8
• 化学式: C₁₅H₁₃ClN₂O₃
• 分子量: 304.733
• InChiKey: LLWLXTMQRMWZIW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.64
• 重原子数：
  21.0
• 可旋转键数：
  4.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.13
• 拓扑面积：
  71.25
• 氢给体数：
  1.0
• 氢受体数：
  5.0

反应信息

• 作为产物：
  描述：

  乙醇 、 5-m-Chlorphenylazo-salicylsaeure 在 硫酸 作用下， 生成 5-(3-chloro-phenylazo)-2-hydroxy-benzoic acid ethyl ester
  参考文献：
  名称：

  Energy balance of hibernating mouse-eared batMyotis myotis: a study with a TOBEC instrument

  摘要：

  We used a non-invasive TOBEC method (Total Body Electric Conductivity) to estimate lean body mass and fat content in mouse-eared bats Myotis myolis (Borkhausen, 1797) hibernating in Poznan Forts (W Poland) and in a semi-natural cave-mine Miedzianka (SE Poland). In December, Fat content averaged 5.5 g in females (body mass = 29.4 g) and 5.3 g in males (body mass = 28.4 g). At the end of hibernation (April), fat content averaged 2.2 g in females (body mass = 25.6 g) and 1.4 g in males (body mass = 23.7 g). Eat content did not differ between the localities either in December or in April, hut the pattern of changes of fat content was different. We calculated the rate of energy expenditure in hibernating bats using two methods, based on independent samples (fat content in first-time captured individuals) and based on paired observations (changes of fat content in re-captured individuals), and discussed problems associated with the two approaches. Both methods show that the bats need about 4.9 g of fat (191 kJ) to sustain a 165-day hibernation. However, the rate of fat usage varied considerably between the sites and hibernation phase. Although the average amount of fat remaining in April would be sufficient to support at least six more weeks of hibernation, the level of reserves was close to zero in some individuals.

  DOI：

  10.1007/bf03192411