([2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)(μ-CO))2 | 477246-90-5

• 英文名称: ([2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)(μ-CO))2
• CAS: 477246-90-5；477178-12-4
• 化学式: C₅₄H₄₄N₂O₄Ru₂
• 分子量: 987.094
• InChiKey: WICVKIDGLNLNKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  二氯甲烷-D2 、 ([2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)(μ-CO))2 以 二氯甲烷-D2 为溶剂， 生成 [2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)2Cl
  参考文献：
  名称：

  Protonated Aminocyclopentadienyl Ruthenium Hydride Reduction of Benzaldehyde and the Conversion of the Resulting Ruthenium Triflate to a Ruthenium Hydride with H₂ and Base

  摘要：

  Reaction of N-phenyl-2,5-dimethyl-3,4-diphenylcyclopenta-2,4-dienimine (6) with Ru3CO12 formed two isomers of {[2,5-Me-2-3,4-Ph-2(eta(5) -C4CNHPh)]Ru(CO)(mu-CO)}(2) (8-trans and 8-cis). Photolysis of 8 under a H-2 atmosphere led to the formation of the aminocyclopentadienyl ruthenium hydride [2,5-Me-2-3,4-Ph-2(eta(5)-C4CNHPh)]Ru(CO)(2)H (9-H). 9-H reduced benzaldehyde slowly at 75 degreesC to give benzyl alcohol and 8. Protonation of 9-H with triflic acid produced {[2,5-Me-2-3,4-Ph-2(eta(5)-C4CNH2Ph)]Ru(CO)(2)H}OTf (11-H), which reacted rapidly with benzaldehyde at -80 degreesC to give benzyl alcohol and [2,5-Me-2-3,4-Ph-2(eta5-C4CNHPh)]Ru(CO)(2)OTf(9-OTf). Reaction of 9-OTf with H2 and base led to the re-formation of 9-H. These reactions provide the transformations required for a catalytic cycle for hydrogenation of aldehydes.

  DOI：

  10.1021/om020507d
• 作为产物：
  描述：

  [2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)2H 在 benzaldehyde 作用下， 以 氘代四氢呋喃 为溶剂， 生成 ([2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)(μ-CO))2
  参考文献：
  名称：

  Protonated Aminocyclopentadienyl Ruthenium Hydride Reduction of Benzaldehyde and the Conversion of the Resulting Ruthenium Triflate to a Ruthenium Hydride with H₂ and Base

  摘要：

  Reaction of N-phenyl-2,5-dimethyl-3,4-diphenylcyclopenta-2,4-dienimine (6) with Ru3CO12 formed two isomers of {[2,5-Me-2-3,4-Ph-2(eta(5) -C4CNHPh)]Ru(CO)(mu-CO)}(2) (8-trans and 8-cis). Photolysis of 8 under a H-2 atmosphere led to the formation of the aminocyclopentadienyl ruthenium hydride [2,5-Me-2-3,4-Ph-2(eta(5)-C4CNHPh)]Ru(CO)(2)H (9-H). 9-H reduced benzaldehyde slowly at 75 degreesC to give benzyl alcohol and 8. Protonation of 9-H with triflic acid produced {[2,5-Me-2-3,4-Ph-2(eta(5)-C4CNH2Ph)]Ru(CO)(2)H}OTf (11-H), which reacted rapidly with benzaldehyde at -80 degreesC to give benzyl alcohol and [2,5-Me-2-3,4-Ph-2(eta5-C4CNHPh)]Ru(CO)(2)OTf(9-OTf). Reaction of 9-OTf with H2 and base led to the re-formation of 9-H. These reactions provide the transformations required for a catalytic cycle for hydrogenation of aldehydes.

  DOI：

  10.1021/om020507d
• 作为试剂：
  描述：

  2-(4,4-dibromobut-3-en-2-yl)-2-(3-methylbut-2-en-1-yl)-1,3-dithiane 在 正丁基锂 、 四溴化碳 、 三丁基膦 、 ([2,5-Me2-3,4-Ph2(η5-C4CNHPh)]Ru(CO)(μ-CO))2 、 碘 、 sodium methylate 、 copper(l) cyanide 、 lithium 、 sodium hydride 、 二异丁基氢化铝 、 碳酸氢钠 、 对甲苯磺酸 、 乙胺 、 三苯基膦 作用下， 以 四氢呋喃 、 甲醇 、 乙醚 、 正己烷 、 二氯甲烷 、 水 、 甲苯 、 乙腈 为溶剂， 反应 55.25h， 生成 panaginsene
  参考文献：
  名称：

  潘加西烯的全合成及结构修订

  摘要：

  通过三亚甲基甲烷（TMM）二基介导的串联环加成反应轻松实现了番石榴粉报道结构的全合成，结果表明合成结构的光谱数据与天然产物的数据不匹配。报道的结构的立体异构体的全合成证实了正确的panaginsene结构是panaginsene最初提出的结构的11- epi立体异构体。

  DOI：

  10.1021/ol500849m

文献信息

• Exploiting the Nucleophilicity of NH Imines: Synthesis of Enamides from Alkyl Azides and Acid Anhydrides
  作者：Junghoon Han、Mina Jeon、Han Kyu Pak、Young Ho Rhee、Jaiwook Park

  DOI：10.1002/adsc.201400584

  日期：2014.9.15

  The nucleophilicity of N‐unsubstituted imines, which were generated from alkyl azides by a ruthenium‐catalyzed reaction, was investigated in the reaction with acid anhydrides. The initial products were N‐acylimines, which isomerized to the corresponding enamides. Heating or triethylamine facilitated the isomerization of N‐acylimines that are stable at room temperature. A wide range of acyclic and cyclic

  在与酸酐的反应中，研究了由烷基叠氮化物通过钌催化反应生成的N-未取代亚胺的亲核性。最初的产物是N-酰亚胺，其异构化为相应的酰胺。加热或三乙胺促进了在室温下稳定的N-酰亚胺的异构化。在温和条件下成功合成了各种含各种官能团的无环和环状酰胺。除乙酸酐外，还可使用各种酸酐。从与环状酸酐的反应中，获得含有羧酸基的酰胺。