N-[1,1,1,4,4,5,5,5-octafluoro-2-(trifluoromethyl)pent-2-en-3-yl]oxypropan-2-imine | 160733-18-6

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 亚胺酰卤
• 英文名称: N-[1,1,1,4,4,5,5,5-octafluoro-2-(trifluoromethyl)pent-2-en-3-yl]oxypropan-2-imine
• CAS: 160733-18-6
• 化学式: C₉H₆F₁₁NO
• 分子量: 353.135
• InChiKey: PBMZMFONWZXIIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.98
• 重原子数：
  22.0
• 可旋转键数：
  3.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  21.59
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  N-[1,1,1,4,4,5,5,5-octafluoro-2-(trifluoromethyl)pent-2-en-3-yl]oxypropan-2-imine 反应 3.0h， 生成 4-hydroxy-3-methyl-5,5-bistrifluoromethyl-2-pentafluoroethyl-1-pyrroline
  参考文献：
  名称：

  Reaction of hexafluoropropylene and its oligomers with acetone oxime

  摘要：

  Reactions of perfluoropropylene and its oligomers with acetone oxime in the presence of a base afford perfluoroalkyl and/or perfluoroalkenyl ethers of acetone oxime. When heated to 100 degrees C, the 3-perfluoro-2-methyl-2-pentenyl ether of acetone oxime (3) is quantitatively converted to 4-hydroxy-3-methyl-5,5-bistrifluoromethyl-4-pentafluoroethyl-1-pyrroline (4), the structure of which was established by X-ray diffraction analysis. A convenient one-stage synthesis of perfluoro-3-isopropyl-4-methyl-3-penten-2-one (7) was proposed.

  DOI：

  10.1007/bf01558067
• 作为产物：
  描述：

  N-[1,1,1,2,2,3,5,5,5-nonafluoro-4-(trifluoromethyl)pentan-3-yl]oxypropan-2-imine 在 氢氧化钾 作用下， 以 乙醚 为溶剂， 反应 0.17h， 以72%的产率得到N-[1,1,1,4,4,5,5,5-octafluoro-2-(trifluoromethyl)pent-2-en-3-yl]oxypropan-2-imine
  参考文献：
  名称：

  Reaction of hexafluoropropylene and its oligomers with acetone oxime

  摘要：

  Reactions of perfluoropropylene and its oligomers with acetone oxime in the presence of a base afford perfluoroalkyl and/or perfluoroalkenyl ethers of acetone oxime. When heated to 100 degrees C, the 3-perfluoro-2-methyl-2-pentenyl ether of acetone oxime (3) is quantitatively converted to 4-hydroxy-3-methyl-5,5-bistrifluoromethyl-4-pentafluoroethyl-1-pyrroline (4), the structure of which was established by X-ray diffraction analysis. A convenient one-stage synthesis of perfluoro-3-isopropyl-4-methyl-3-penten-2-one (7) was proposed.

  DOI：

  10.1007/bf01558067