| 1242142-73-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并二恶英
• CAS: 1242142-73-9
• 化学式: C₂₂H₁₆O₈
• 分子量: 408.364
• InChiKey: GAVOVDYRKNRGPO-UHFFFAOYSA-N

反应信息

• 作为反应物：
  描述：

  、 N,N-二甲基乙二胺 在 silica gel 作用下， 以 二氯甲烷 为溶剂， 反应 18.0h， 以70%的产率得到
  参考文献：
  名称：

  Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

  摘要：

  New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.

  DOI：

  10.2174/157017810790796291
• 作为产物：
  描述：

  丁炔二酸二甲酯 、 2-(1,4-benzodioxin-2-yl)-1,4-benzodioxin 以 甲苯 为溶剂， 反应 4.0h， 以82%的产率得到Dimethyl 5a,7a-dihydro-[1,4]benzodioxino[3,2-a]oxanthrene-6,7-dicarboxylate
  参考文献：
  名称：

  Benzoxazine and Benzodioxine as Indole Isosteres in Indolocarbazoles Series: Synthesis and Biological Evaluation

  摘要：

  New series of structure based on original benzodioxine and benzoxazine heterocycles were prepared leading to potential anticancer lead compounds. In this paper, we described a convenient approach via a Diels-Alder cycloaddition in order to efficiently provide three new indole isosteres in indolocarbazoles series. Their first cytotoxic evaluation was also reported.

  DOI：

  10.2174/157017810790796291