m-Trigallussaeure-methylester | 4724-91-8

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: m-Trigallussaeure-methylester
• 英文别名: 5-((2,3-Dihydroxy-5-(methoxycarbonyl)phenoxy)carbonyl)-2,3-dihydroxyphenyl 3,4,5-trihydroxybenzoate；[5-(2,3-dihydroxy-5-methoxycarbonylphenoxy)carbonyl-2,3-dihydroxyphenyl] 3,4,5-trihydroxybenzoate
• CAS: 4724-91-8
• 化学式: C₂₂H₁₆O₁₃
• 分子量: 488.361
• InChiKey: CRISSNCDOBZMQI-UHFFFAOYSA-N

物化性质

• 沸点：
  877.0±65.0 °C(Predicted)
• 密度：
  1.724±0.06 g/cm3(Predicted)

文献信息

• Inhibitors of D-amino acid oxidase (DAAO) and uses thereof
  申请人：SyneuRx International (Taiwan) Corp.

  公开号：US10927138B2

  公开（公告）日：2021-02-23

  Provided herein are compounds of Formula (I) and uses thereof for inhibiting the activity of D-amino acid oxidase (DAAO) or treating diseases or disorders associated with DAAO, such as a central nervous system (CNS) disorder, obesity, diabetes, or hyperlipidemia. Also provided in the present disclosure are methods of synthesizing the Formula (I) compounds described herein.

  本文提供了式(I)化合物及其用途，用于抑制D-氨基酸氧化酶（DAAO）的活性或治疗与DAAO相关的疾病或紊乱，如中枢神经系统（CNS）紊乱、肥胖、糖尿病或高脂血症。本公开还提供了合成所述式（I）化合物的方法。
• INHIBITORS OF D-AMINO ACID OXIDASE AND USES THEREOF
  申请人：SyneuRx International (Taiwan) Corp.

  公开号：US20210214385A1

  公开（公告）日：2021-07-15

  Provided herein are potent compounds of Formula (I) and uses thereof for inhibiting the activity of D-amino acid oxidase (DAAO) or treating diseases or disorders associated with DAAO, such as a central nervous system (CNS) disorder, pain, obesity, diabetes, or hyperlipidemia. Also provided in the present disclosure are methods of synthesizing the Formula (I) compounds described herein. (I)
• [EN] COMPOUNDS AND PHARMACEUTICAL USES THEREOF<br/>[FR] COMPOSÉS ET LEURS UTILISATIONS PHARMACEUTIQUES
  申请人：SYNEURX INT TAIWAN CORP

  公开号：WO2021155864A1

  公开（公告）日：2021-08-12

  A method of treating coronavirus infection, comprising administering to a subject in need thereof an effective amount of a composition, wherein the composition comprises one or more compounds of Formula (I), or a pharmaceutically acceptable salt thereof.