The present invention relates to novel thienopyrimidine compounds of general formula
pharmaceutical compositions comprising these compounds and their therapeutic use for the prophylaxis and/or treatment of diseases which can be influenced by the inhibition of the kinase activity of Mnk1 and/or Mnk2 (Mnk2
a
or Mnk2
b
) and/or variants thereof.
本发明涉及新型
噻吩并
嘧啶化合物,其一般公式,包含这些化合物的药物组合物,以及它们在预防和/或治疗可通过抑制Mnk1和/或Mnk2(Mnk2a或Mnk2b)及其变体的激酶活性而影响的疾病中的治疗用途。