tri-n-butylstannyl-2-[4-(diethylamino)arylazo]benzenecarboxylate | 149312-49-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: tri-n-butylstannyl-2-[4-(diethylamino)arylazo]benzenecarboxylate
• 英文别名: Tributylstannyl 2-[[4-(diethylamino)phenyl]diazenyl]benzoate
• CAS: 149312-49-2
• 化学式: C₂₉H₄₅N₃O₂Sn
• 分子量: 586.405
• InChiKey: ZHWZHNQIWUXXCX-UHFFFAOYSA-M

物化性质

• 沸点：
  601.2±65.0 °C(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  9.45
• 重原子数：
  35
• 可旋转键数：
  17
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.55
• 拓扑面积：
  54.3
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  三丁基氧化锡 、 乙基红 以 苯 为溶剂， 生成 tri-n-butylstannyl-2-[4-(diethylamino)arylazo]benzenecarboxylate
  参考文献：
  名称：

  Synthesis, microbiological study and X-ray structural characterisation of a tri-n-butylstannyl-2[4(diethylamino)arylazo]benzenecarboxylate

  摘要：

  Organostannyl carboxylates adopt an interesting range of structural variations leading to different structure-activity relationship. Organostannyl-2(arylazo)benzenecarboxylates, reported here, inhibit Gram-positive bacterial growth with an average MIC 10-20 mug ml(-1), which is below the lethal dose. The discrete molecular units of this series of compounds function as an anisobidentate chelating ligand, thus rendering the Sn atom five coordinated and adopt a polymeric form. The present work reports the X-ray crystallographic structure of tri-n-butylstannyl-2[4(diethylamino)arylazo]benzenecarboxylate and microbial studies in order to get insight into the mode of action of such compounds in biology. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0022-328x(01)01350-x