1-Phenyl-cyclopentanecarboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 托烷生物碱
• 英文名称: 1-Phenyl-cyclopentanecarboxylic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl ester
• 英文别名: (8-methyl-8-azabicyclo[3.2.1]octan-3-yl) 1-phenylcyclopentane-1-carboxylate
• 化学式: C₂₀H₂₇NO₂
• mdl: MFCD02737450
• 分子量: 313.4
• InChiKey: WQIVCNLLAVUHIE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.4
• 重原子数：
  23
• 可旋转键数：
  4
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.65
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Tropane derivatives, their synthesis and their use
  申请人：MOBIL OIL CORPORATION

  公开号：EP0195498A2

  公开（公告）日：1986-09-24

  This invention is directed to novel quaternary ammonium tropane compounds and 3-substituted derivatives thereof and their synthesis. The compounds are novel compounds having valuable utility as organic directing agents in the crystallization of various silicates, which, in turn, are useful, as catalyst components, sorbents, and/or ion-exchangers. More particularly, this invention is concerned with quaternary ammonium tropane compounds and 3-substituted derivatives thereof synthesized by selective alkylation of the bridgehead nitrogen of tropane or 3-substituted derivatives thereof.

  本发明涉及新型季铵托烷化合物及其 3-取代衍生物和它们的合成。这些化合物是新型化合物，在各种硅酸盐的结晶过程中可用作有机引导剂，而硅酸盐又可用作催化剂成分、吸附剂和/或离子交换剂。更具体地说，本发明涉及通过选择性烷基化托烷的桥头氮或其 3-取代衍生物而合成的季铵托烷化合物及其 3-取代衍生物。
• US5614629A
  申请人：——

  公开号：US5614629A

  公开（公告）日：1997-03-25