4-(4-methoxyphenyl)-thiomorpholine 1,1-dioxide | 82222-72-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 噻嗪类
• 英文名称: 4-(4-methoxyphenyl)-thiomorpholine 1,1-dioxide
• 英文别名: 4-(4-Methoxyphenyl)-1,4-thiazinane 1,1-dioxide
• CAS: 82222-72-8
• 化学式: C₁₁H₁₅NO₃S
• 分子量: 241.311
• InChiKey: BUSRIFZVJGOSHN-UHFFFAOYSA-N

物化性质

• 熔点：
  146.0-148.1 °C
• 沸点：
  481.4±40.0 °C(predicted)
• 密度：
  1.255±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二乙烯基砜 、 4-硝基苯甲醚 在 indium 、 溶剂黄146 作用下， 以 甲醇 为溶剂， 反应 24.0h， 以48%的产率得到4-(4-methoxyphenyl)-thiomorpholine 1,1-dioxide
  参考文献：
  名称：

  One-Pot Aryl-1,4-thiomorpholine 1,1-Dioxide Synthesis via Double 1,4-Addition of in situ Reduced Nitroarenes to Divinyl Sulfones

  摘要：

  One-pot reduction-triggered double aza-Michael type 1,4-addition reactions of various nitroarenes to divinyl sulfones were investigated. In the presence of indium/AcOH in MeOH or in sat. aq NH(4)Cl/MeOH, nitroarenes and divinyl sulfones were cyclized to give 1,4-thiomorpholine 1,1-dioxides.

  DOI：

  10.3987/com-09-11858

文献信息

• COMPOUND OR ITS TAUTOMER, METAL COMPLEX COMPOUND, COLORED PHOTOSENSITIVE CURING COMPOSITION, COLOR FILTER, AND PRODUCTION
  申请人：MIZUKAWA Yuki

  公开号：US20120238752A1

  公开（公告）日：2012-09-20

  Provided is a colored photosensitive curing composition useful for color filters in primary colors, including blue, green, and red, having a high molar absorption coefficient and allowing a reduction in film thickness and superior color purity and fastness. A colored photosensitive curing composition, comprising, as its colorant, a dipyrromethene-based metal complex compound obtained from a metal or metal compound and a dipyrromethene-based compound represented by the following Formula (I): wherein in Formula (I), R 1 to R 6 each independently represent a hydrogen atom or a substituent group; and R 7 represents a hydrogen or halogen atom, or an alkyl, aryl or heterocyclic group.

  提供的是一种有用于原色彩色滤光片的彩色光敏固化组合物，包括蓝色、绿色和红色，具有高摩尔吸收系数，可减少薄膜厚度，具有优越的颜色纯度和牢固度。 一种彩色光敏固化组合物，包括作为其着色剂的从金属或金属化合物获得的基于二吡咯甲烷的金属配合物化合物和由以下式（I）表示的基于二吡咯甲烷的化合物，其中在式（I）中，R1至R6各自独立地表示氢原子或取代基；R7表示氢或卤素原子，或烷基、芳基或杂环基。
• Reagentless Chemistry “On-Water”: An Atom-Efficient and “Green” Route to Cyclic and Acyclic β-Amino Sulfones via aza-Michael Addition Using Microwave Irradiation
  作者：Soumik Saha、Amrita Chatterjee、Mainak Banerjee

  DOI：10.1021/acs.joc.3c01855

  日期：2023.11.3

  was developed for facile access to cyclic and acyclic β-amino sulfones “on-water” using a microwave. A variety of aromatic and aliphatic amines undergo double aza-Michael addition on the surface of the water with water-insoluble divinyl sulfones upon microwave irradiation at 150 °C for 10 min to mostly afford solid cyclic β-amino sulfones as easily separable products in excellent yields by simple filtration

  开发了一种无试剂、无催化剂且可持续的方法，可以使用微波轻松地“在水上”获得环状和无环 β-氨基砜。在 150 °C 微波照射 10 分钟后，各种芳香族和脂肪族胺与水不溶性二乙烯基砜在水表面进行双氮杂迈克尔加成，大部分得到固体环状 β-氨基砜，作为易于分离的产品，具有优异的性能。通过简单过滤即可获得产量，避免任何后处理步骤。因此，基材的所有原子都反映在产品中，使其成为 100% 原子效率的方法。富电子胺和缺电子胺都很好地参与了反应，并且观察到良好的官能团耐受性。竞争性实验预期揭示了富电子胺更快的反应动力学。通过以类似的方式使苯基/乙基乙烯基砜与各种胺相互作用，该方法扩展到无环 β-氨基砜。正如预期，该方法提供了非常低的环境因素（在 0.05-0.5 范围内）和较高的 Ecoscale 得分（高达 94）。为了实现可持续发展，这种无试剂、无金属、无有机溶剂、具有成本效益的方案无疑是现有 β-氨基砜方法的可行替代方案。
• Aminomercuration-Demercuration of Divinyl Sulfone: Synthesis of 4-Aryltetrahydro-1,4-thiazine 1,1-Dioxides
  作者：J. Barluenga、C. Jiménez、C. Nájera、M. Yus

  DOI：10.1055/s-1982-29820

  日期：——
• BARLUENGA, J.;JIMENEZ, C.;NAJERA, C.;YUS, M., SYNTHESIS, BRD, 1982, N 5, 417-419
  作者：BARLUENGA, J.、JIMENEZ, C.、NAJERA, C.、YUS, M.

  DOI：——

  日期：——
• Compound or its tautomer, metal complex compound, colored photosensitive curing composition, color filter, and production
  申请人：Mizukawa Yuki

  公开号：US20080076044A1

  公开（公告）日：2008-03-27

  Provided is a colored photosensitive curing composition useful for color filters in primary colors, including blue, green, and red, having a high molar absorption coefficient and allowing a reduction in film thickness and superior color purity and fastness. A colored photosensitive curing composition, comprising, as its colorant, a dipyrromethene-based metal complex compound obtained from a metal or metal compound and a dipyrromethene-based compound represented by the following Formula (I): wherein in Formula (I), R 1 to R 6 each independently represent a hydrogen atom or a substituent group; and R 7 represents a hydrogen or halogen atom, or an alkyl, aryl or heterocyclic group.