4-[[4-[[8-[4-[[4-(dimethylamino)phenyl]diazenyl]phenyl]sulfonyl-1,4,8,11-tetrazacyclotetradec-1-yl]sulfonyl]phenyl]diazenyl]-N,N-dimethylaniline | 1258205-10-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 偶氮苯
• 英文名称: 4-[[4-[[8-[4-[[4-(dimethylamino)phenyl]diazenyl]phenyl]sulfonyl-1,4,8,11-tetrazacyclotetradec-1-yl]sulfonyl]phenyl]diazenyl]-N,N-dimethylaniline
• CAS: 1258205-10-5
• 化学式: C₃₈H₅₀N₁₀O₄S₂
• 分子量: 775.012
• InChiKey: WEWFAWJSUYPORJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.3
• 重原子数：
  54
• 可旋转键数：
  10
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.37
• 拓扑面积：
  172
• 氢给体数：
  2
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  1,4,8,11-四氮杂环十四烷 、 4-二甲胺基苯基偶氮苯磺酰氯 在 三乙胺 作用下， 以 氯仿 为溶剂， 反应 11.0h， 以48%的产率得到4-[[4-[[8-[4-[[4-(dimethylamino)phenyl]diazenyl]phenyl]sulfonyl-1,4,8,11-tetrazacyclotetradec-1-yl]sulfonyl]phenyl]diazenyl]-N,N-dimethylaniline
  参考文献：
  名称：

  Recognition of Hg²⁺ Using Diametrically Disubstituted Cyclam Unit

  摘要：

  A newly synthesized 1,4,8,11-tetraazacyclotetradecane derivative (L), functionalized with a diazo moiety as the reporter functionality, is found to bind specifically to Hg2+ with an associated change in color that could be visually detected. With biologically benign beta-CD, it forms an inclusion complex (L center dot 2 beta-CD), which shows a much higher solubility in water, and this helps in developing a more intense color on binding to Hg2+ in a CH3CN-HEPES buffer medium. The nontoxic nature of L was checked with the living cells of a Gram negative bacterium, Pseudomonas putida. Further, experiments revealed that these two reagents could be used as staining agents for the detection of Hg2+ present in this microorganism.

  DOI：

  10.1021/ic1014797

文献信息

• Recognition of Hg²⁺ Using Diametrically Disubstituted Cyclam Unit
  作者：Prasenjit Mahato、Amrita Ghosh、Sukdeb Saha、Sandhya Mishra、Sanjiv K. Mishra、Amitava Das

  DOI：10.1021/ic1014797

  日期：2010.12.20

  A newly synthesized 1,4,8,11-tetraazacyclotetradecane derivative (L), functionalized with a diazo moiety as the reporter functionality, is found to bind specifically to Hg2+ with an associated change in color that could be visually detected. With biologically benign beta-CD, it forms an inclusion complex (L center dot 2 beta-CD), which shows a much higher solubility in water, and this helps in developing a more intense color on binding to Hg2+ in a CH3CN-HEPES buffer medium. The nontoxic nature of L was checked with the living cells of a Gram negative bacterium, Pseudomonas putida. Further, experiments revealed that these two reagents could be used as staining agents for the detection of Hg2+ present in this microorganism.