2-Diphenylphosphanylethyl ethyl hydrogen phosphate | 874270-20-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: 2-Diphenylphosphanylethyl ethyl hydrogen phosphate
• CAS: 874270-20-9
• 化学式: C₁₆H₂₀O₄P₂
• 分子量: 338.28
• InChiKey: NSQFGMQGSLJUJB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  22
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  55.8
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  ethyl ethylene phosphate 、 sodium diphenylphosphide 以 四氢呋喃 为溶剂， 生成 2-Diphenylphosphanylethyl ethyl hydrogen phosphate
  参考文献：
  名称：

  Ambident Electrophilicity of 5-Membered Ring Phosphate Triesters

  摘要：

  The reactions of 2-alkoxy-1,3,2-dioxaphospholane 2-oxide with various nucleophiles were studied both experimentally and theoretically. These studies show that 5-membered ring phosphate triesters act as ambident electrophiles: hard and bulky nucleophiles attack at the phosphorus while soft nucleophiles attack at the ring carbon.

  DOI：

  10.1080/10426500701735452

文献信息

• Ambident Electrophilicity of 5-Membered Ring Phosphate Triesters
  作者：Nissan Ashkenazi、Yoffi Segall、Yishai Karton、Sanjio S. Zade、Michael Bendikov

  DOI：10.1080/10426500701735452

  日期：2008.1.14

  The reactions of 2-alkoxy-1,3,2-dioxaphospholane 2-oxide with various nucleophiles were studied both experimentally and theoretically. These studies show that 5-membered ring phosphate triesters act as ambident electrophiles: hard and bulky nucleophiles attack at the phosphorus while soft nucleophiles attack at the ring carbon.