cis-2-methoxy-4-methyl-1,3,2-dioxaphosphinane 2-oxide | 103959-30-4

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: cis-2-methoxy-4-methyl-1,3,2-dioxaphosphinane 2-oxide
• 英文别名: 4-methyl-2-methoxy-1,3,2-dioxaphosphorinane 2-oxide；2-methoxy-4r-methyl-[1,3,2]dioxaphosphinane 2t-oxide；(2S*,4S*)-2-Methoxy-4-methyl-[1,3,2]dioxaphosphinane 2-oxide；(2R,4S)-2-methoxy-4-methyl-1,3,2λ5-dioxaphosphinane 2-oxide
• CAS: 103959-30-4
• 化学式: C₅H₁₁O₄P
• 分子量: 166.114
• InChiKey: JYAHVSACNISFOW-XUOSJQGZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  cis-2-methoxy-4-methyl-1,3,2-dioxaphosphorinane 在 二甲基氧化硒 作用下， 以 氯仿 为溶剂， 生成 cis-2-methoxy-4-methyl-1,3,2-dioxaphosphinane 2-oxide
  参考文献：
  名称：

  Organosulfur compounds. 14. Dimethyl selenoxide oxidation of trivalent phosphorus compounds, thio- and selenophosphoryl compounds, and thiocarbonyl compounds. Stereochemical studies and selective modification of the thiocarbonyl-containing nucleic acid components

  摘要：

  DOI：

  10.1021/jo00405a010

文献信息

• Stereoretentive conversion of cyclic phosphorothioates into [18O]phosphates using [18O]chloral
  作者：Andrzej Okruszek、Wojciech J. Stec

  DOI：10.1039/c39840000117

  日期：——

  P-Chiral cyclic dialkyl phosphorothioates are converted into the corresponding P-chiral[18O]phosphates by [18O]chloral with retention of configuration at phosphorus.

  P-手性环状二烷基硫代磷酸酯通过[ 18 O]氯醛转化为相应的P-手性[ 18 O]磷酸盐，并保留了磷的构型。
• A General Method for the Conversion of Thiophosphoryl and Selenophosphoryl Groups into Phosphoryl Groups by Ozone Oxidation
  作者：Aleksandra Skowronska、Ewa Krawczyk

  DOI：10.1055/s-1983-30407

  日期：——
• Synthesis of polyfluoralkylated 1,3,2-dioxaphospholane and 1,3,2-dioxaphosphorinane oxides
  作者：N. K. Gusarova、S. I. Verkhoturova、S. N. Arbuzova、T. I. Kazantseva、A. I. Albanov、A. M. Nalibaeva、G. K. Bishimbaeva

  DOI：10.1134/s107042801711001x

  日期：2017.11

  Polyfluoroalkyl dichlorophosphates easily react with 1,2- or 1,3-alkanediols in a system pyridine-diethyl ether and afford 2-polyfluoroalkoxy-1,3,2-dioxaphospholane oxides or 2-polyfluoroalkoxy-1,3,2-dioxaphosphorinane oxides. In similar conditions the reaction of methyl dichlorophosphate with 1,2- and 1,3-alkanediols proceeds less effectively.
• Oxygen-17 NMR spectra of cyclic phosphites, phosphates, and thiophosphates
  作者：Ernest L. Eliel、Subramanian. Chandrasekaran、Leslie E. Carpenter、John G. Verkade

  DOI：10.1021/ja00281a034

  日期：1986.10
• A new method of phosphorus-selenium bond cleavage. Stereocontrolled synthesis of P-chiral phosphoric-trifluoroacetic anhydrides
  作者：Lucyna A. Wozniak、Bozenna Krzyzanowska、Wojciech J. Stec

  DOI：10.1021/jo00048a050

  日期：1992.10