TPAP | 35687-90-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磷酸及其衍生物
• 英文名称: TPAP
• 英文别名: Tripropylamine phosphate；N,N-dipropylpropan-1-amine;phosphoric acid
• CAS: 35687-90-2
• 化学式: C₉H₂₁N*H₃O₄P
• 分子量: 241.268
• InChiKey: FEBXQZCZEKDGEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  90.7
• 氢给体数：
  3
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  三正丁胺 、 3'-O-methyl-N7-methylguanosine-5'-monophosphate 、 TPAP 在 甲醇 、 N,N'-羰基二咪唑 作用下， 以 水 、 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以30%的产率得到7-methyl-3'-O-methylguanosine 5-bisphosphate
  参考文献：
  名称：

  Synthesis and Application of a Chain-Terminating Dinucleotide mRNA Cap Analog

  摘要：

  We describe the synthesis of a chain-terminating mRNA cap dinucleotide and its use in the in vitro transcription of homogeneously capped RNA. Computer modeling strongly indicates that RNA capped with the new compound will be a substrate for cap-dependent translation.

  DOI：

  10.1021/ol0167715
• 作为产物：
  描述：

  三正丁胺 在 磷酸 作用下， 以 二氯甲烷 为溶剂， 反应 1.5h， 生成 TPAP
  参考文献：
  名称：

  Synthesis and Application of a Chain-Terminating Dinucleotide mRNA Cap Analog

  摘要：

  We describe the synthesis of a chain-terminating mRNA cap dinucleotide and its use in the in vitro transcription of homogeneously capped RNA. Computer modeling strongly indicates that RNA capped with the new compound will be a substrate for cap-dependent translation.

  DOI：

  10.1021/ol0167715
• 作为试剂：
  描述：

  tri-N-propylammonium adenosine 5'-dithiophosphoromorpholidate 在 TPAP 作用下， 以 吡啶 为溶剂， 反应 6.5h， 以25%的产率得到adenosine 5'-(α,α-dithio)diphosphate
  参考文献：
  名称：

  进一步的研究与腺苷5 ' -dithiophosphoromorpholidate。通过“三酯”方法方便地制备核苷二硫代磷酸酯

  摘要：

  腺苷5 ' -dithiophosphoromorpholidate 1c中发生反应以正磷酸盐，得到腺苷5 ' -（α，α-二硫代）二磷酸3c中但不转化为腺苷5 ' -phosphorodithioate 2c中通过酸性水解。描述了一种合成核苷二硫代磷酸酯的新方法。

  DOI：

  10.1016/j.tetlet.2004.01.135

文献信息

• Hydration of alpha-Pinene to obtain alpha-terpineol, using an ionic liquid as solvent, which is synthesized from a tertiary amine and an inorganic acid
  申请人：Centro de Investigación en Materiales Avanzados, S.C.

  公开号：US20210170379A1

  公开（公告）日：2021-06-10

  An ionic liquid as a solvent in the hydration reaction of α-pinene to α-terpineol. The ionic liquid is obtained from the reaction of an amine and an inorganic acid. The use of the ionic liquid as solvent favors the selectivity towards the formation of α-terpineol and once the reaction product has been brought to room temperature, the organic phase can be physically separated from the inorganic one by decantation. The inorganic phase contains the ionic liquid, water and reaction catalyst and can be directly reused for a new reaction batch.

  一种离子液体作为α-蒎烯水合反应中的溶剂。该离子液体是由胺和无机酸反应得到的。使用离子液体作为溶剂有利于选择性生成α-蒎烯醇，一旦反应产物降至室温，有机相可以通过倾析与无机相分离。无机相包含离子液体、水和反应催化剂，可以直接用于新的反应批次。
• Sheet-like heating elements and preparation thereof
  申请人：Japat Ltd

  公开号：EP0560721A2

  公开（公告）日：1993-09-15

  A sheet-like heating element using an electrically conductive polymer complex consisting of a) a polycation of polyheteroaromatic compound ; and b) a polyanion of thermoplastic polymer, containing a sulfated alcohol group in the repeating structural unit, having film-forming properties.

  一种使用导电聚合物复合物的片状加热元件，该聚合物复合物包括 a) 聚芳香族化合物的聚阳离子；和 b) 热塑性聚合物的聚阴离子，其重复结构单元中含有硫酸化醇基，具有成膜特性。
• Solid electrolytic capacitors and process for producing the same
  申请人：Japat Ltd

  公开号：EP0571329A2

  公开（公告）日：1993-11-24

  A solid electrolytic capacitor having a solid electrolyte layer, which layer comprises an electrically conductive thermoplastic organic polymer complex having an electric conductivity of 0.1 Scm-1 or more and a glass transition temperature of -100 to 150°C formed on a valve metal foil through a dielectric film. A small and larege-capacity solid electrolytic capacitor having excellent highfrequency characteristic and long-term stability is provided.

  一种固体电解电容器具有固体电解质层，该层由导电性热塑性有机聚合物复合物组成，其导电率为 0.1 Scm-1 或以上，玻璃化温度为 -100 至 150°C，通过电介质膜形成在阀金属箔上。本发明提供的固体电解电容器体积小、容量大，具有出色的高频特性和长期稳定性。
• Electrochemical based assay processes instrument and labels
  申请人：Jones, Mark Howard

  公开号：EP0962773A1

  公开（公告）日：1999-12-08

  A method for quantitating or detecting an analyte using an electrochemical reaction, comprising a material in contact with an electrolyte in a cell or chamber but not in electronic contact with an external electronic circuit, at least some of said material having at least its surface conducting or semi-conducting, and applying a voltage gradient across at least a portion of said material, the size of said material, the conductivity of said electrolyte and/or reactant liquid and the voltage gradient being such that not only are anodic and cathodic faces established in respect of at least some of the conducting or semi-conducting material, rendering said material bipolar, the electropotentials so generated are such that said electrochemical reaction takes place on at least a portion of the surfaces of said material resulting in the production of a detectable signal or detectable material. The said bipolar material which, advantageously, are spherical or fibres, may comprise solid conducting or semi-conducting material or cores of non-conducting material with coatings of conducting or non-conducting material thereon. The material, which are preferably in suspension, may also be bound or captured directly or indirectly onto a surface or filter matrix. The said surface or filter matrix if conducting is not acting as an electrode to carry out electrochemistry. The detection of the electrochemically-generated signal or material is related to the quantity or presence of said analyte.

  一种利用电化学反应定量或检测分析物的方法，包括在电池或反应室中与电解液接触但不与外部电子电路接触的材料，所述材料的至少部分至少表面导电或半导电，在所述材料的至少部分上施加电压梯度，所述材料的尺寸、所述电解质和/或反应液的导电性以及电压梯度不仅能在至少部分导电或半导电材料上形成阳极和阴极面，使所述材料成为双极材料，而且所产生的电势能使所述电化学反应在所述材料的至少部分表面上发生，从而产生可检测信号或可检测材料。上述双极材料最好是球状或纤维状，可包括固体导电或半导电材料，或带有导电或非导电材料涂层的非导电材料芯。这些材料最好处于悬浮状态，也可以直接或间接地结合或捕捉到表面或过滤基质上。上述表面或过滤基质如果导电，则不作为进行电化学反应的电极。电化学产生的信号或材料的检测与所述分析物的数量或存在有关。
• Composition for film formation, method of film formation, and silica-based film
  申请人：JSR CORPORATION

  公开号：US20030091838A1

  公开（公告）日：2003-05-15

  A composition for film formation which comprises: (A) a product of hydrolysis and condensation obtained by hydrolyzing and condensing at least one silane compound selected from the group consisting of compounds represented by the formula (1), compounds represented by the formula (2), and compounds represented by the formula (3) in the presence of water and an ammonium compound, and (B) an organic solvent.

  一种用于成膜的组合物，它包括 (A) 至少一种硅烷化合物的水解和缩合产物，该硅烷化合物选自由式（1）、式（2）和式（3）所代表的化合物组成的组，在水和铵化合物存在下水解和缩合得到，以及 (B) 有机溶剂。