1,6-dioxa-cyclodeca-3,8-diene | 22464-27-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 奥昔康唑
• 英文名称: 1,6-dioxa-cyclodeca-3,8-diene
• 英文别名: (3Z,8Z)-2,5,7,10-Tetrahydro-[1,6]dioxecin；cis,cis-1,6-Dioxa-3,8-cyclodecadien；4,9-Dioxacyclodecadien-(1,6)；1,6-Dioxacyclodeca-3,8-dien；(3Z,8Z)-2,5,7,10-tetrahydro-1,6-dioxecine
• CAS: 22464-27-3
• 化学式: C₈H₁₂O₂
• 分子量: 140.182
• InChiKey: PKEKPUOKXKLBDX-LOKDLIDFSA-N

物化性质

• 沸点：
  216.7±40.0 °C(Predicted)
• 密度：
  0.959±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  3,6-bis(trifluoromethyl)-1,2,4,5-tetrazine 、 1,6-dioxa-cyclodeca-3,8-diene 在 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 生成
  参考文献：
  名称：

  Pericyclic Domino reactions with 3,6-Bis(trifluoromethyl)-1,2,4,5-tetrazine: A convenient entry into azo cage compounds

  摘要：

  3,6-Bis(trifluoromethyl)-1,2,4,5-tetrazine (1) characterized by a highly reactive, electron deficient diazadiene system reacted with several cyclic and acyclic bis-dienophiles to yield the cage compounds 11, 19a,b, 31a,b and 41 in a pericyclic homo-domino reaction in good yields. The first step of the domino reactions is an inverse electron demand intermolecular Diels-Alder addition followed by elimination of nitrogen to give 4,5-dihydropyridazines which then undergo a terminaI ring closure to yield the cage compounds. The solvent employed and the reaction temperature is of crucial importance. Whereas in nitromethane and at elevated temperatures the main products are the cage compounds, at lower temperature and in dichloromethane as solvent the initially formed 4,5-dihydropyridazines are frequently converted to 1,4-dihydropyridazines by a 1,3-H-shift. Treatment of the tetrazine 1 with cyclooctatriene 23 did not lead to a cage compound in any case; instead via valence tautomeric species octa-1,3,5,7-tetraene 23a and bicyclo[4.2.0]octa-2,4-diene 23b the twofold pyridazine-substituted butadienes 24 and 26 together with the tricyclic cyclobuta[f]phthalazine 25 were formed.

  DOI：

  10.1002/prac.199733901111
• 作为产物：
  描述：

  顺式-1,2-二羟甲基乙烯 、 顺式-1,4-二氯-2-丁烯 在 四氢呋喃 、 sodium hydroxide 作用下， 生成 1,6-dioxa-cyclodeca-3,8-diene
  参考文献：
  名称：

  Reppe et al., Justus Liebigs Annalen der Chemie, 1955, vol. 596, p. 1,132

  摘要：

  DOI：

文献信息

• Haftklebemassen mit hohen Molmassen und enger Molmassenverteilung und Verfahren zu deren Herstellung
  申请人：tesa AG

  公开号：EP2607394A1

  公开（公告）日：2013-06-26

  Die Erfindung betrifft ein Verfahren zur Herstellung von Haftklebemassen, welche hohe Molmassen kombiniert mit einer engen Molmassenverteilung aufweisen, sowie entsprechend hergestellte Haftklebemassen besonders Polyacrylat-basierende Haftklebemassen. Überraschender Weise wurde gefunden, dass Polymere mit hohen Molmassen und einer engen Molmassenverteilung, insbesondere Polyacrylate mit hohen Molmassen und einer engen Molmassenverteilung, hervorragend insbesondere mittels RAFT-Verfahren in Anwesenheit eines Diradikal-Initiators, welcher thermisch unter Ausbildung eines Diradikals cyklisiert, herstellen lassen und welche Zur Verwendung als scherfeste Haftklebemassen geeignet sind.

  本发明涉及一种生产具有高分子量和窄分子量分布的压敏胶组合物的工艺，以及相应生产的压敏胶组合物，特别是以聚丙烯酸酯为基础的压敏胶组合物。 令人惊奇的是，研究人员发现，具有高分子量和窄分子量分布的聚合物，特别是具有高分子量和窄分子量分布的聚丙烯酸酯，可以在有二元引发剂存在的情况下，特别是通过 RAFT 工艺生产出来，这种工艺通过热循环形成二元引发剂，适合用作抗剪切压敏胶组合物。
• POLYETHER POLYMER AND PRODUCTION PROCESS THEREOF
  申请人：Ihata Osamu

  公开号：US20110065889A1

  公开（公告）日：2011-03-17

  A polyether polymer containing a defined polymerization unit (—R 1 —O—R 2 —O—), R 1 and R 2 being derived from monomers (A) and (B), respectively; and a process for producing the polyether polymer comprising the step of copolymerizing the monomer (A) with the monomer (B) in the presence of a metal salt, wherein the monomer (A) is (A1) a non-conjugated mono-cyclic diene compound containing a cyclic skeleton, or (A2) a non-conjugated cyclic diene compound containing a mutual linking of plurality of a mono-cyclic structure having a cyclic skeleton, and the monomer (B) is an aliphatic diol, an alicyclic diol or a divalent phenol.
• US8487071B2
  申请人：——

  公开号：US8487071B2

  公开（公告）日：2013-07-16
• Pericyclic Domino reactions with 3,6-Bis(trifluoromethyl)-1,2,4,5-tetrazine: A convenient entry into azo cage compounds
  作者：Thilo Klindert、Peter von Hagel、Luzian Baumann、Gunther Seitz

  DOI：10.1002/prac.199733901111

  日期：——

  3,6-Bis(trifluoromethyl)-1,2,4,5-tetrazine (1) characterized by a highly reactive, electron deficient diazadiene system reacted with several cyclic and acyclic bis-dienophiles to yield the cage compounds 11, 19a,b, 31a,b and 41 in a pericyclic homo-domino reaction in good yields. The first step of the domino reactions is an inverse electron demand intermolecular Diels-Alder addition followed by elimination of nitrogen to give 4,5-dihydropyridazines which then undergo a terminaI ring closure to yield the cage compounds. The solvent employed and the reaction temperature is of crucial importance. Whereas in nitromethane and at elevated temperatures the main products are the cage compounds, at lower temperature and in dichloromethane as solvent the initially formed 4,5-dihydropyridazines are frequently converted to 1,4-dihydropyridazines by a 1,3-H-shift. Treatment of the tetrazine 1 with cyclooctatriene 23 did not lead to a cage compound in any case; instead via valence tautomeric species octa-1,3,5,7-tetraene 23a and bicyclo[4.2.0]octa-2,4-diene 23b the twofold pyridazine-substituted butadienes 24 and 26 together with the tricyclic cyclobuta[f]phthalazine 25 were formed.
• Reppe et al., Justus Liebigs Annalen der Chemie, 1955, vol. 596, p. 1,132
  作者：Reppe et al.

  DOI：——

  日期：——