4-nitro-benzoic acid-(2-tert-butyl-phenyl ester)

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: 4-nitro-benzoic acid-(2-tert-butyl-phenyl ester)
• 英文别名: 4-Nitro-benzoesaeure-(2-tert-butyl-phenylester)；p-Nitrobenzoic acid, O-t-butylphenyl ester；(2-tert-butylphenyl) 4-nitrobenzoate
• 化学式: C₁₇H₁₇NO₄
• 分子量: 299.326
• InChiKey: SXWPYUXWUDGMRA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.24
• 拓扑面积：
  72.1
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2-叔丁基苯酚 生成 4-nitro-benzoic acid-(2-tert-butyl-phenyl ester)
  参考文献：
  名称：

  Prospective LASIK trial for myopia and myopic astigmatism: 1-year results

  摘要：

  A prospective, nonrandomized, unmasked, 1-year clinical trial was performed in 2482 eyes to evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) for myopia and myopic astigmatism using a new excimer laser system. The study found that LASIK was a safe and effective method for correcting myopia and myopic astigmatism in patients with sphere to −15 diopters (D) and cylinder to 5 D.

  DOI：

  10.1007/s12009-001-0047-4

文献信息

• Prospective LASIK trial for myopia and myopic astigmatism: 1-year results
  作者：Frederic B. Kremer、George Pronesti、John Sloat、Pater Calla

  DOI：10.1007/s12009-001-0047-4

  日期：2001.12

  A prospective, nonrandomized, unmasked, 1-year clinical trial was performed in 2482 eyes to evaluate the safety and efficacy of laser in situ keratomileusis (LASIK) for myopia and myopic astigmatism using a new excimer laser system. The study found that LASIK was a safe and effective method for correcting myopia and myopic astigmatism in patients with sphere to −15 diopters (D) and cylinder to 5 D.