3α-Tigloyloxytropan | 536697-11-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 托烷生物碱
• 英文名称: 3α-Tigloyloxytropan
• 英文别名: Tigloidine；(8-methyl-8-azabicyclo[3.2.1]octan-3-yl) (E)-2-methylbut-2-enoate
• CAS: 536697-11-7
• 化学式: C₁₃H₂₁NO₂
• 分子量: 223.315
• InChiKey: UVHGSMZRSVGWDJ-RUDMXATFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.5
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.77
• 拓扑面积：
  29.5
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• METHOD OF SENSITIZING CANCER CELLS TO THE CYTOTOXIC EFFECTS OF DEATH RECEPTOR LIGANDS IN CANCER TREATMENT
  申请人：Sayers Thomas Joseph

  公开号：US20130039883A1

  公开（公告）日：2013-02-14

  Disclosed is a method of enhancing the response of cancer cells in a mammal to treatment with a death receptor ligand, which method comprises contacting the cancer cells with a death receptor ligand in conjunction with an effective amount of a compound described herein, for example, a cucurbitacin (I) or a withanolide (II). Also disclosed is a method of inducing apoptosis in cancer cells in a mammal, comprising contacting the cancer cells with a compound described herein, for example, a cucurbitacin (I) or a withanolide (II) and also contacting the cancer cells with a death receptor ligand, whereby apoptosis is induced in the cancer cells.
• Method of Improving the Growth and Production Output of Plants of the Family Solanaceae
  申请人：Ankner Charles E.

  公开号：US20170280643A1

  公开（公告）日：2017-10-05

  A method and system of improving the growth of plants belonging to the family Solanaceae by providing a plant nutrient solution about the plant roots and a gas mixture circulating about the plant shoot; by selecting the gas mixture and plant nutrient solution temperature independently of the other; and providing a plant nutrient solution to gas mixture temperature differential of approximately at least approximately 10° F. during different phases of plant development. The method and system improves plant development to improve a desired plant organ for industrial, scientific, and medical purposes. A method of improving the growth and development of Solanaceae plants by providing a shoot-to-root temperature differential to treat or prevent infection by a plant pathogen and/or infestation by pests.
• US6866872B1
  申请人：——

  公开号：US6866872B1

  公开（公告）日：2005-03-15
• US7790905B2
  申请人：——

  公开号：US7790905B2

  公开（公告）日：2010-09-07
• US7927613B2
  申请人：——

  公开号：US7927613B2

  公开（公告）日：2011-04-19