Phenyl 4-bromo-2-butoxy-5-fluoro-6-methyl-3-[(2-methylpropan-2-yl)oxycarbonyl-prop-2-enylamino]benzoate

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 缩酚酸和缩酚酸环醚类
• 英文名称: Phenyl 4-bromo-2-butoxy-5-fluoro-6-methyl-3-[(2-methylpropan-2-yl)oxycarbonyl-prop-2-enylamino]benzoate
• 英文别名: phenyl 4-bromo-2-butoxy-5-fluoro-6-methyl-3-[(2-methylpropan-2-yl)oxycarbonyl-prop-2-enylamino]benzoate
• 化学式: C₂₆H₃₁BrFNO₅
• 分子量: 536.4
• InChiKey: FYWBUGACRPKRIV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  34
• 可旋转键数：
  12
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  65.1
• 氢给体数：
  0
• 氢受体数：
  6

文献信息

• Tetracycline Compounds
  申请人：Tetraphase Pharmaceuticals, Inc.

  公开号：US20160107988A1

  公开（公告）日：2016-04-21

  The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use.
• Tetracyline Compounds
  申请人：Tetraphase Pharmaceuticals, Inc.

  公开号：US20170305852A1

  公开（公告）日：2017-10-26

  The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use.
• US9573895B2
  申请人：——

  公开号：US9573895B2

  公开（公告）日：2017-02-21
• [EN] TETRACYCLINE COMPOUNDS<br/>[FR] COMPOSÉS DE TÉTRACYCLINES
  申请人：TETRAPHASE PHARMACEUTICALS INC

  公开号：WO2014036502A2

  公开（公告）日：2014-03-06

  The present invention is directed to a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof. The variables for Structural Formula (I) are defined herein. Also described is a pharmaceutical composition comprising the compound of Structural Formula (I), or a pharmaceutically acceptable salt thereof, and its therapeutic use.